Top Tweets for #AxSPA
๐ Take Home Messages from the early #axSpA session
๐บ Earlier diagnosis is possible and better
๐บ Early axSpA is not synonymous to mild
๐บ Longitudinally, early axSpA is heterogeneous
๐บ MRI has transformed the field
โ๏ธBeware of pitfalls
#EULAR2026 @RheumNow
SELECT-Axis 2 trial and Withdrawal of Upadacitinib - Of 734 pts, 194 were in remission at wk104--> UPA w/d & 22% maintained drug-free remission for >48wks. Rest flared, median time to flare: 3.1 mos (89% regained LDA by wk24 w/ restart) #EULAR2026 #axSpA POS1350
๐ Take Home Messages from the early #axSpA session
๐บ Earlier diagnosis is possible and better
๐บ Early axSpA is not synonymous to mild
๐บ Longitudinally, early axSpA is heterogeneous
๐บ MRI has transformed the field
โ๏ธBeware of pitfalls
#EULAR2026 @RheumNow
#EULAR2026 LB0002 More great news for dual IL17A and -F blockade. An open label Phase II study of Sonelokimab, a novel IL-17A- and IL-17F-inhibiting Nanobody'-3 in #axSpA: clinical efficacy, improvement in PROM and imaging inflammation. Looking forward to the RCT phase @RheumNow
LB0002: Sonelokimab (IL-17A/F Nanobody, ~40 kDa) in #axSpA Phase 2: 81% ASAS40 and 54% ASAS partial remission at 12 weeks. Mean ASDAS improvement of โ2.0 from baseline. @RheumNow #EULAR2026
ASAS-SPARTAN #AxSpA classification criteria 2025
โ ๏ธ MRI needs to have inflammatory PLUS structural lesions
#EULAR2026 @Official_ASAS #sacroilitis #IBD #Uveitis #enthesitis
Which b/tsDMARDs are effective in #axSpA? Stratified by extramusculoskeletal manifestations
Check out the latest update of the treatment heatmap ๐ฅ
By Astrid van Tubergen
At axial and peripheral SpA at a crossroads session
#EULAR2026
@RheumNow
Which b/tsDMARDs are NOT effective in #axSpA?
Check out the latest update of the treatment heatmap ๐ฅ
By Astrid van Tubergen
At axial and peripheral SpA at a crossroads session
#EULAR2026
@RheumNow
Which b/tsDMARDs are effective in #axSpA?
Check out the latest update of the treatment heatmap ๐ฅ
By Astrid van Tubergen
At axial and peripheral SpA at a crossroads session
#EULAR2026
@RheumNow
Gecacitinib (pan-JAK inhibitor) vs placebo in radiographic #axSpA ASAS40 51.9% vs 12.9% (p<0.0001) at 16 weeks. ASAS20 69.2% vs 21.2% (p<0.0001). Pan-JAK inhibition showed efficacy in TNFi-experienced patients. Abstr OP0240 @RheumNow #EULAR2026
Treat-to-target in inflammatory arthritis recommended by every guideline. Followed in only 40% of SpA visits.
The main reason was activity simply wasnโt documented using a validated index.
You canโt target what you donโt measure.
Abstr 0351 @ RheumNow #EULAR2026
#axSpA #PsA #Rheumatology
#EULAR2026: phase 2 S-OLARIS data on sonelokimab in axSpA showed >80% ASAS40 by wk 12, with PET/MRI evidence of reduced inflammation and osteoblast activity. Chatting with Xenofon Baraliakos, MD, on Friday.
https://t.co/cSkf40wmz5 #AxSpA #Rheumatology
โIt can be tough to say no and it is tough to pace yourself in a world that is constantly on the goโฆ Having an #invisibleillness requires a complete lifestyle change and you canโt really understand it unless you are ill.โ https://t.co/YEKURDb2zn @globetrotteri #axSpA #pwME #cpp
CyTOF reveals significant sexual dimorphism in monocyte populations in active #axSpA
Women show reduced classical and non-classical monocytes vs healthy controls. Men do not show the same pattern.
Sex is not just a demographic variable in AxSpA it is also an immunological one.
Abstr POS0082 at #EULAR2026 @RheumNow
Ivarmacitinib (selective JAK1 inhibitor) significantly improved ASAS40 vs placebo in nr-#axSpA(39.7% vs 24.8%; p=0.006) at 12 weeks, sustained to 24 weeks. Another oral option for non-radiographic disease. Abstr OP0237 @RheumNow #EULAR2026
โก Can #tofacitinib induce remission in early #axSpA?
FASTLANE (Phase 4 RCT, n=107)
YES! ASDAS inactive disease 26.4% vs 7.4% placebo at Wk16
#OP0241 #EULAR2026 @RheumNow
At #EULAR2026, conversations on the ground are focused on how to achieve and maintain disease control in #PsA and #axSpA. AbbVie is on-site, sharing new research and a commitment to improving patient outcomes. Learn more: https://t.co/H2rNBLvGuV
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