Top Tweets for #BasicClinicals
🦴 It occurs commonly to patients who have been treated for hypercalcemia caused by bone demineralization disorders, parathyroid diseases, thyotoxicosis and vitamin D deficiency.
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To be continued…
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☢️ There’s a classic triad in one-third of cases— BED
B- Bone (calvarial) defect
E- Exophthalmos
D- Diabetes insipidus
It may become systemic and prognosis is variable.
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☑️ This interaction is absolutely required for platelet adhesion and subsequent aggregation at the site of injury.
The absence of platelet aggregation results in failure of the blood coagulation cascade.
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🌐 Drugs that can cause this similar reaction (Disulfiram like reaction) include Antibiotics (metronidazole, cephalosporin), Antifungals (griseofulvin), etc.
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🔍 There may also be signs of autonomic dysfunction such as pupillary abnormalities, an abnormal reaction to intradermal histamine, abnormal sweating, orthostatic hypotension, and disturbances of the heart rate.
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▪️Treat infections as appropriate.
▪️Cardiac management is primarily medical.
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➡️ Methods of performing autopsy:
▪️Lettulle method
▪️Virchow method
▪️Rokistansky method
▪️Ghon method
▪️Evisceration method
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🔷 RISK FACTORS
▪️Pregnant woman
▪️Well fed infant
▪️Under 5 years
▪️Travelers from malaria non-endemic area
💊 TREATMENT
▪️I.V Artesunate
▪️I.V Quinine
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📍 AMSTEL CRITERIA of diagnosis of bacteria vaginosis :
🔹Clue cells on microscopy
🔸Creamy greyish white vaginal discharge
🔹Vaginal pH >4.5
🔸Fishy odour on adding 10% KOH
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...the macula.
📍This characteristic damage can be caused by several aetiologies such as inherited retinal conditions, long-term use of drugs such as chloroquine and hydroxylchloroquine, amongst other causes.
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🔹It is symptomatic in infancy but later improves with age
📌 Other common links between people with TAR seem to include anemia, heart problems, kidney problems, knee joint problems, and frequently milk allergy.
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BCl Thursday💊👨🏽💼👩🏻
💥RED MAN SYNDROME
aka red neck syndrome
Red man syndrome is the most common adverse reaction to the drug Vancomycin.
💡The name comes from the red rash that develops on the face, neck, and torso of affected people.
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...severe intellectual disability, developmental disability, speaking problems, balance and movement problems, seizures, and sleep problems.
▪️The symptoms generally become noticeable by one year of age.
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BCl Thursday💊👨🏽💼👩
💥ALPERS DISEASE
This is a progressive disease of the nervous system characterized by spasticity (tightness), myoclonus, dementia and liver problems with jaundice and cirrhosis.
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BCl Thursday💊👨🏽💼👩
💥Evans Syndrome
Evans syndrome is the coexistence of simultaneous or sequential direct Coombs-positive autoimmune hemolytic anemia (AIHA) with immune-mediated thrombocytopenia.
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