Top Tweets for #BioRXIV
๐ขWe are excited to share our latest bioRxiv preprint from the Biton Lab!
We identify CD45 as a tuft cellโintrinsic negative regulator of intestinal type 2 immunity
We'd love to hear your thoughts and feedback!
๐ https://t.co/Dq39rQriSl
#bioRxiv #MucosalImmunity #TuftCells
New preprint on #bioRxiv ๐งต We first showed that ablating the choroid plexus cuts CSF production in ROSA26-iDTR mice. Now weโve engineered an AAV5-DTR vector that does this robustly in both neonatal and adult animals!
New manuscript Estimating Cardiac 5-HT2B Safety Margins for Repeated Low-Dose Psilocybin Using an Exposure-Response Model #preprint posted on @biorxivpreprint #biorxiv #psilocybin
https://t.co/UefB6sRY8Z
3. NPBdetect predicted 417 (ODOG) and 298 (IndeNCBI) high-confidence antibacterial BGCs.
4. Genomic surveillance enables tracking of antimicrobial resistance genes across bacterial genomes.
#bioRxiv #GenomeMining #Bioinformatics
Fascinating new influenza immune evasion mechanism: PA-X suppresses IFN-ฮป, inflammatory cytokines, and MHC I in the human airway, potentially reducing CD8โบ T-cell recognition. https://t.co/xqMeTYEfFn
#Influenza #Immunology #Virology #bioRxiv
Excited to share our preprint on OASSIS, an oil-free, open digital bioassay platform. Combining aqueous two-phase reactors with CRISPR-Cas13a enables amplification-free RNA detection and serial sample loading to improve sensitivity. https://t.co/E6oG3jsY49
#bioRxiv
Can your microscope resolve the structure you want to study before you run the experiment?
New #bioRxiv preprint: VLab4Mic predicts structural resolvability in #SuperResolution microscopy, helping choose modality and probe.
Great work from @HenriquesLab.
@RTsuperES ; @EUeic @JDamianMtzR
https://t.co/od0u6X9kBT
More of the BANC team are on the blue butterfly site than X - a fuller list is over there! Note, #biorxiv version of the paper: https://t.co/m1gnWwOgNq 18/18
Everything's public ๐
๐งโ๐ป Code: https://t.co/vXjcBLuzoj
๐ค Weights: https://t.co/bBkeZX1EAC
๐ฆ pip install tessera-foundation
๐พ TCGA representations on Zenodo: https://t.co/bumGHCPdCv
Can't wait to see how people build on this ๐
#bioRxiv
Stoked that the project I started as soon as I started my PhD with @tfadgreef is finally out on #bioRxiv! ๐
Huge effort. ๐ช๐ผIt took a village to raise that baby! ๐ถ ๐ฅฐ
I came in knowing nothing about synthetic receptors (my background was #microRNAs). Tomโs idea to add a miRNA negative feedback loop to #synNotch -the way nature does it-finally became reality with my amazing co-first authors Bryan Nathalia ๐ฆธ and Tom Meuleman ๐จโ๐ฌ.
We built a self-limiting, tunable system where activated synNotch induces its own repressor and autonomously attenuates signaling over time.
Really excited about the bigger picture here: embedding this kind of autonomous control has the potential to make engineered cells more predictable, tunable, and adaptive โ exactly what weโll need for safer, smarter cell therapies.
Huge thanks to Bryan, Tom, and the whole team at TU/e, Utrecht University & MIT.
Preprint ๐ https://t.co/9jjHh6dUfL
#SyntheticBiology #CellEngineering #synNotch
Excited to share our preprint on autonomous feedback control in synthetic receptor systems.
We engineered a miRNA-based negative feedback circuit where synNotch activation drives expression of a synthetic miRNA that represses the receptor itself.
Preprint: https://t.co/JIEP59vjjb
Very excited to get this new work by Shin Ngiow up on #bioRxiv. We may be blocking PD-1 too long causing detrimental effects on Tpex cells. A drug holiday approach may be beneficial. Also some cool new Tpex biology here. #immunopharmacology https://t.co/TjkOE423Gu
We Figure Out How SARS-CoV-2 Induces Thrombosis - Johnson Mak
https://t.co/NF0GDqnVCr
#BioRxiv #Glycan #Health #Hematology #Hemostasis #HemostasisNews #HemostasisToday #Medicine #SARSCoV2 #SialicAcid #Thrombosis #MedEd #MedX
In this #bioRXiv article, J Dearani, MD, @SteveOmmen, @jeffreygeske and other experts discuss a multi-omics atlas of sex-specific differences in obstructive HCM.
https://t.co/mwYo6vgcGM
New Insights into Pediatric Stroke and Neuroinflammation from Kuan and Sun Labs - Melissa Kinkaid
https://t.co/ebuZJJlJGv
#BioRxiv #Health #Hematology #Hemostasis #HemostasisNews #HemostasisToday #Medicine #Neuroinflammation #PediatricStroke #Thrombosis #MedEd #MedX
gbpA and chiA genes are not uniformly distributed amongst diverse Vibrio cholerae published as: https://t.co/UDzA3W7WQr @MicrobioSoc #biorxiv
Reliable identification of protein-protein interactions by crosslinking mass spectrometry published as: https://t.co/xtyvgwqEji @naturecomms #biorxiv
Ribosome stalling caused by the Argonaute-microRNA-SGS3 complex regulates the production of secondary siRNAs in plants published as: https://t.co/9kgnO0cXgv @cellreports #biorxiv
๐จ New preprint alert! ๐จ A study 6 years in the making, made possible by funding from @SimonsFdn: "A multi-omic atlas in the African turquoise killifish reveals increased glucocorticoid signaling as a hallmark of brain aging" up on #biorXiv https://t.co/s8O7DG1kEY a ๐งต 1/11
Genome-wide analysis in Escherichia coli unravels an unprecedented level of genetic homoplasy associated with cefotaxime resistance. published as: https://t.co/IHfrONjmeI @MicrobioSoc #biorxiv
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