Top Tweets for #BroadTalks
Great to see a new online publication for women >45 headed up by the wonderful @marinasgo Today, interview with @Kate_Jenkins_ (keep an eye out for @BroadAgenda #BroadTalks series - coming up). Good luck with #tonic (all team members worked together at Dolly - back in the day)
"How do genes control our size and shape?" Watch the video of @joelhirschhorn giving the Eliana Hechter Lecture to find out: https://t.co/FyLRYfybXn #broadtalks
.@DrAnneCarpenter's Midsummer Nights' Science talk will be posted on the Broad YouTube channel later this week. #broadtalks
More on utility of cell painting for disease research: https://t.co/rWfBPgLp8u #broadtalks
Carpenter: In studies, compounds selected for testing that were chosen by image analysis outperformed ones chosen by experts #broadtalks
Drugs can be chosen for assays based on features identified in computer image analysis #broadtalks 2/2
Transforming drug discovery via Cell Painting: Measure healthy & disease cells, treat w/ compounds, observe. 1/2 #broadtalks
Carpenter: Computers can also help compare cell populations. Humans not great at distinguishing features among 1000s of cells #broadtalks
#CellProfiler can scan treated cells at scale, as well as measure complex phenotypes difficult to quantify w/ naked eye. #broadtalks
When biologists know what they're looking for, they look at cells & "score" them to teach software distinguishing features. 2/2 #broadtalks
Carpenter: First step in process = measure everything, then use #machinelearning to "score" a cell. 1/2 #broadtalks
.@DrAnneCarpenter talked to @sciencemagazine about 'cell painting' and image analysis last year: https://t.co/51QYHRXByj #broadtalks
What can you learn from image analysis? Cell size, shape, DNA abundance, mitochondrial abundance... just to name a few features. #broadtalks
.@DrAnneCarpenter's lab is employing #CellProfiler to measure cell properties in disease and drug discovery. #broadtalks
CellProfiler identifies, measures, counts various features of cells at a scale humans couldn't do. https://t.co/So3qTTXxq6 #broadtalks
Carpenter used to measure cell images manually as postdoc. "I grew up on a farm. It was honestly the best summer job I ever had" #broadtalks
If you have questions for @DrAnneCarpenter, share them w/ #broadtalks. We'll try to get to them during tonight's Q&A.
@DrAnneCarpenter: Robots increase speed at which biologists can screen compounds, cells. #broadtalks
Carpenter: Broad has library of a few hundred thousand compounds; use multi-well plates to screen many compounds at once. #broadtalks
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