Top Tweets for #CONDUCTAF

about 1 month ago

🔴 #CONDUCTAF at #HF2026 N=82 HFrEF pts with symptomatic refractory AF, EF<50%, narrow QRS, NT-proBNP >600 Randomised 1:1 to Conduction System Pacing (LBBAP→HBP→BVP) vs Biventricular Pacing + AVNA Double-blind, non-inferiority design 🎯 Primary endpoint: ΔLVEF at 6 months Results to follow 👇 #CardioTwitter #HeartFailure26

$drbennisahmed's tweet photo. 🔴 #CONDUCTAF at #HF2026 N=82 HFrEF pts with symptomatic refractory AF, EF<50%, narrow QRS, NT-proBNP >600 Randomised 1:1 to Conduction System Pacing (LBBAP→HBP→BVP) vs Biventricular Pacing + AVNA Double-blind, non-inferiority design 🎯 Primary endpoint: ΔLVEF at 6 months Results to follow 👇 #CardioTwitter #HeartFailure26$

470

Ahmed Bennis MD 🫀 @drbennisahmed

about 1 month ago

🧵 BREAKING | #CONDUCTAF trial results just presented at #HeartFailure26 by David Žižek (Ljubljana, Slovenia) — a late-breaking science moment! 🫀 1/ The question: Conduction system pacing (CSP/LBBAP) vs. biventricular pacing (BVP) after AV node ablation in HF patients with refractory AF and narrow QRS. First ever RCT on this! (NCT05467163) 2/ Background: CSP via left bundle branch area pacing (LBBAP) offers procedural advantages over His bundle pacing in the AVNA context — but prior evidence comparing CSP to BVP was only observational. Time for an RCT. ✅ 3/ Primary endpoint — LVEF change at 6 months: 📊 Mean difference: 0.4% (95% CI: −3.1 to 3.8) ✅ Non-inferiority met (p=0.002, margin 5%) ➡️ CSP was non-inferior to BVP for LV recovery 4/ Key findings: 🔵 Similar structural reverse remodelling 🔵 Similar functional capacity, QoL & clinical outcomes 🔵 LBBAP showed a more favourable procedural profile + narrower paced QRS 5/ Bottom line: LBBP is a viable alternative to BVP in a ‘pace and ablate’ strategy. Whether CSP offers incremental benefit on hard clinical endpoints needs larger, longer RCTs. Watch this space! 👀 #Cardiology #HFchat #HeartFailure #PaceAndAblate #LBBAP #ConductionSystemPacing

$drbennisahmed's tweet photo. 🧵 BREAKING | #CONDUCTAF trial results just presented at #HeartFailure26 by David Žižek (Ljubljana, Slovenia) — a late-breaking science moment! 🫀 1/ The question: Conduction system pacing (CSP/LBBAP) vs. biventricular pacing (BVP) after AV node ablation in HF patients with refractory AF and narrow QRS. First ever RCT on this! (NCT05467163) 2/ Background: CSP via left bundle branch area pacing (LBBAP) offers procedural advantages over His bundle pacing in the AVNA context — but prior evidence comparing CSP to BVP was only observational. Time for an RCT. ✅ 3/ Primary endpoint — LVEF change at 6 months: 📊 Mean difference: 0.4% (95% CI: −3.1 to 3.8) ✅ Non-inferiority met (p=0.002, margin 5%) ➡️ CSP was non-inferior to BVP for LV recovery 4/ Key findings: 🔵 Similar structural reverse remodelling 🔵 Similar functional capacity, QoL & clinical outcomes 🔵 LBBAP showed a more favourable procedural profile + narrower paced QRS 5/ Bottom line: LBBP is a viable alternative to BVP in a ‘pace and ablate’ strategy. Whether CSP offers incremental benefit on hard clinical endpoints needs larger, longer RCTs. Watch this space! 👀 #Cardiology #HFchat #HeartFailure #PaceAndAblate #LBBAP #ConductionSystemPacing$

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