Top Tweets for #CalR
@harrisoncn1 41c) 3⃣ Maturing data from the #FIC Fc silent mutant #CALR targeting #INCA033989 ➡️impressive evidence of disease modification in #MF, inc #anemia response. Watch for Ph 3 trials hopefully in 1st as well as later lines of therapy. More data to come w/other agents in this space
@harrisoncn1 28) In the trial, spleen & symptom responses were impressive for a largely 2L population where baseline scan was taken pre-JAKi washout. Note there were populations of JAKi experienced & naïve pts, & different types of #CALR mutations are called out with colors indicating dose.
👏👏👏Outstanding MPN oral session at #EHA26 #EHA2026 !!!!! With our growing global 🌍 #MPNSM community of researchers! #JAK2 #CALR #MPL #KIT #hepcidin | @mpdrc @harrisoncn1 @SKordasti @KordastiL @beth_psaila @pankitvachhani @AdamMead_Oxford
#EHA26 #EHA2026 Prof @harrisoncn1 presents the second oral presentation of MPN session @EHA_Hematology 👉 #CALR mAB for patients with Myelofibrosis | #MPNSM
👏👏👏 Lovely to meet up with wonderful colleagues & hear their updates on their research from all over the 🌍 thanks to @EHA_Hematology !! #EHA26 #EHA2026 🙏 @beth_psaila @jyoti_nangalia | #BPDCN #leusm #MPNSM #CALR
Continuing #ESHMPN2026 with #MeetTheExpert sessions.
Great insight and discussion with @TheElfLab about #CALR, the mechanisms within the cell and the arising new therapies.
#MPN #CARTcell #Monoclonal
#ESHCONFERENCES
📣#ESHMPN2026: STARTS THIS FRIDAY!
LAST CHANCE TO REGISTER! ➡ https://t.co/r6busR9sOn
11th Translational Research Conference
Myeloproliferative Neoplasms
April 24-26 in Estoril, Portugal
Chairs: @jjkiladjian, @rosslevinemd, @MullallyLab, @jyoti_nangalia
#ESHCONFERENCES #MPNsm
👉👉👉Grateful to have the opportunity to serve as invited speaker & to present about MPNs : Targeting mutant #CALR & mutant #JAK2 at the annual @MDEducation MPN-MDS meeting ! 🙏 to @Ryan_Fitzpatric @bose_prithviraj @Ramikomrokji & team for the kind invitation | #MPNSM |
🧬 This gene plays a role in the proper folding of proteins within the cell.
Its function helps maintain balance in various cellular processes related to blood production.
An example of how small variations can influence the hematological system.
#CALR #MPN #Scientific
Amer Hayat Shares New BSH Guideline of Investigation and Management of Thrombocytosis
@Aamer_Hayyat
https://t.co/j1JkjnG0rG
#BSHGuideline #Health #Hemostasis #HemostasisToday #JAK2 #Medicine #MPL #Thrombosis #BSH #CALR #MedEd #MedX
4) And now, we’re off!
So what is #myelofibrosis #MF? It is a is a clonal stem cell disorder where mutations (#JAK2, #CALR, #MPL) drive bone marrow fibrosis, disrupting normal blood cell production ➡️ extramedullary #hematopoiesis—often in the spleen.
👉Fantastic translational MPN talk by Dr @TheElfLab on Type 1 vs Type 2 #CALR mutations in #MPNSM !!! @TheIACH @MpncoD | @harrisoncn1 @mpdrc @doctorpemm |
👉Wonderful talk 👏 by Dr .@TheElfLab on Targeting #CALR mutations Type I vs Type 2 | #BCLxL | #MPNWorkshop25 #MPNSM | @LindaResar @mpdrc @AmiBPatelMD
The incomparable @TheElfLab teaching us about therapeutic vulnerabilities in Type 1 vs Type 2 #CALR mutated #MF #MPNs #GodmotherOfCALR
👉👉👉Superb start to our #MPNWorkshop25 meeting in Charlotte NC co-founded by @mpdrc + @doctorpemm ! Great opportunity for discussion for new ideas 💡 in the field of MPN ! #MPNSM #inflammation #leusm #BPDCN #cytokines #JAK2 #CALR #thrombosis | @sanamloghavi @MpncoD @HemeReports
Can we target mutant CALR in MPNs for real disease modification?
In this podcast episode, the experts discuss:
🧬 Therapeutic antibodies
🧫 Cellular therapies
🔍 Trial updates
🎧 A must-listen for HCPs in hemonc: https://t.co/HuaEL3ZJK9
#MPN #CALR #HemOnc #Myelofibrosis
👉👉👉Important concepts to consider together as we aim for #DiseaseModification in MPNs in Developing a potential new era ➡️ moving beyond #JAKi monotherapy | #MPNSM #bmtsm #ImmunoOnc #CALR #TargetedTherapy | @AdamMead_Oxford @HemeReports @VJHemOnc @MPN_Hub @MpncoD @MPN_RF
🎙️ New VJHemOnc podcast episode
Explore the potential for disease modification in CALR-mutated MPNs using antibody & cell-based therapies.
🔗 Listen now: https://t.co/DWL8Y1rrcM
#MPN #HemOnc #Myelofibrosis #CALR
#EHA2025 #EHA25 | Nice talk by Dr Isabelle Plo on #CALR & #CALR-directed therapies current & future directions | @EHA_Hematology
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