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$RHHBY CVRM pipeline progressing. $ALNY $ZEAL $ETNB #Carmot
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$RHHBY Pharma Day 2025. Hypertension, Obesity and MASH (metabolic space) key focus in the next ten years. More deals to come? $ETNB $ZEAL $ALNY $ROIV #Carmot https://t.co/MBME9J9r7j
1/5
Why did Roche do the largest licence deal in history for a single molecule when they did a deal for $ZEAL amylin Petrelintide?
If we look at Petrelintide 16w data, the highest dose 9mg only delivered 8.3% WL. Thatโs anything than great data. So why did Roche do the deal?
Well when companies release a PR, we only get high level data. But when we dig deeper, we can see the data actually is much better than what the PR stated.
At EASD ZEAL showed data at gender level. Below is for the 9mg top dose group.
PR said 9.0mg WL 8.3%
Sub data
2 women 14.6% WL
8 men 6.8% WL
$ZEAL $LLY $NVO $VKTX $GUBRA
$RHHBY #Carmot CT-173 (PYY analogue) decision to discontinue development. $NVO $LLY $ZEAL $VKTX https://t.co/HXC2Dd5YBt
Today is car M.O.T day. And, I hate it! The drop off, the trip home, the lengthy wait and then the dreaded call! Cut to delight if it passes but doom, if it doesnโt. Urghhhhh! ๐ #CarMOT
$ZEAL Appoints Eric Cox as Chief Commercial Officer. Interesting: Eric was at #Carmot, which was acquired by $RHHBY in December 2023. $NVO $LLY $VKTX $GUBRA https://t.co/GKkpoX0OHT
@bio_clouseau @BertrandBio That was the pipeline of #Carmot when #Roche $RRHBY announced the acquisition back December. $VKTX $NVO $LLY
#Carmot $RHHBY - cc: $NVO $LLY $VKTX
Roche/Carmot detailed efficacy data for CT-388 looking good; abstract does not detail safety data yet (to come at oral presentation on 12 September) but states โno product related discontinuationsโ and GI adverse events described as only โmild to moderateโ. @BertrandBio
Roche/Carmot detailed efficacy data for CT-388 looking good; abstract does not detail safety data yet (to come at oral presentation on 12 September) but states โno product related discontinuationsโ and GI adverse events described as only โmild to moderateโ. @BertrandBio
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