Top Tweets for #DefinedDailyDose
Defined Daily Dose ππ
DDD 99- In medically stable patients with prosthetic joint infections, withholding antimicrobial therapy for at least 2 weeks prior to collecting synovial fluid for culture increases likelihood of recovering an organismπ¦
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Defined Daily Dose ππ
DDD 98- Antibiotic lock technique is an effective and safe option for both prevention & treatment of catheter related bloodstream infections(CRBSI), however should be used in conjunction with systemic antimicrobial therapy.
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Defined Daily Dose ππ
DDD 97- Cefiderocol is an injectable cephalosporin, similar to ceftazadime & cefepime but has enhanced stability to beta lactamases including AmpC & ESBLs as it enters periplasmic space due to siderophore like activity.
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Defined Daily Dose ππ
DDD 96- With the current infodemic in competition with the pandemic, it is our social responsibility to educate people. So all you doctors i.e the reliable sources, please get onto social media, do your bit!π
Sharing=Caring!
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Defined Daily Dose ππ
DDD 95- Therapeutic efficacy =Susceptibility Breakpoint MIC/MIC of the isolate
Higher the therapeutic efficacy better the antibiotic,also keep other PK-PD factors while starting therapy.
Go beyond S/I/R.
Go beyond MIC.
ππ
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Defined Daily Dose ππ
DDD 94- Gram stain has a high negative predictive value for diagnosing Ventilator associated pneumonia, almost 94%.Always ask for one. Absence of pus cells will help you rule out VAP, also gives you the presumptive pathogenπ
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New original research published in the @EJHP_bmj that evaluates the interest of a #DefinedDailyDose (DDD) based analysis in the evaluation of pain management in the #EmergencyDepartment read it here: https://t.co/IFPYYc31uf
#Hospital #Pharmacy #anaelgesic
Defined Daily Dose ππ
DDD 93- Acyclovir administration must be accompanied by adequate hydration. Intravenous infusion of the antiviral must be given over a period of at least one hour to reduce risk of renal tubular damage.
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Defined Daily Dose ππ
DDD 92- The mainstay therapy for cholera is rehydration, but the addition of antibiotics can decrease the severity and duration of illness in critically ill clients.
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Defined Daily Doseππ
DDD 91- For surgical antibiotic prophylaxis use the shortest effective single dose antibiotic with a long enough half-life to achieve activity throughout the surgery.
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Defined Daily Doseππ
DDD 90- The volume of blood in the blood culture set is the most significant variable in recovering organisms in bloodstream infections. Ensure adequate volume is collected. As you sowπ©Έ so shall you reapπ¦
π
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Defined Daily Doseππ
DDD 89- Laboratory technicians play a very important role in Antimicrobial Stewardship &Infection Control activities. Motivate & mentor them, quality testing & reporting in Microbiology & ID is only because of them.
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Defined Daily Doseππ
DDD 88- AMSP Turn around time is the time when decision is made to ask for a culture to the time the culture & antibiotic susceptibility report is used for therapy, this is the most important TAT in antibiotic stewardship.
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Defined Daily Doseππ
DDD 87- The use of Rifampin as a single agent or as adjunctive therapy for the treatment of skin and soft tissue infections is not recommended.
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Defined Daily Doseππ
DDD 86- Atovoqone is a 2nd line therapy when CD4 Count is < 200/mm3 for Pneumocystis infection if cotrimoxazole therapy fails. Complications like pulmonary oedema, pneumothorax & opportunistic infections should be excluded.
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Defined Daily Doseππ
DDD 85- Anidulafungin is unique among echinocandins because it slowly degrades in plasma, undergoing a process of biotransformation rather than being metabolized. It is effective in fluconazole-refractory mucosal candidiasis.
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Defined Daily Doseππ
DDD 84-Microbiology is as clinical as Cardiology or Orthopedics,all you Microbiologists out there stop being paraclinical.See slides & petri plates, step out of the lab to the wards and see your patients.They deserve the care.
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Defined Daily Dose ππ
DDD 83- Time-dependent antimicrobials like beta lactams have maximal microbiological effect when their
concentrations are maintained above MIC for as long as possible throughout the dosing interval.
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Defined Daily Doseππ
DDD 82-Fidaxomicin is an oral macrolide antibiotic used for the treatment of C. difficile associated diarrhea in adults. It is contraindicated for systemic infections, to be used only for proven or strongly suspected cases.
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Defined Daily Doseππ
DDD 81-Formulary restrictions for high end antibiotics is one of the front end strategies of Antimicrobial Stewardship. 'Out of sight is out of mind' can be applied here, what is not easy to procure is not easy to prescribe.
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