Top Tweets for #Erythroid
How erythroid progenitor cells and mature red blood cells shape immunity
In this review, Dr. Shokrollah Elahi of @UAlberta highlights how #erythroid cells actively regulate immune responses, shaping immunity across infection, cancer, and inflammation.
π https://t.co/y1Qj0unhxI

.@jboerckel, @AmiLang_Science, and team identify #erythroid precursors as active regulators of local oxygen availability in the #BoneMarrow niche, which may be targetable to enhance tissue regeneration.
π More in @PNASNews: https://t.co/pg1uCOJZEW

Researchers performed single-cell RNA sequencing to analyze #hematopoietic stem and progenitor cells and #erythroid cells in a mouse model of high-altitude polycythemia mimicking long-term high-altitude hypoxia exposure. | @CellStemCell
π Check it out: https://t.co/1XiH0sN8oB

Today in @sigtrans_sttt! π‘
Using primary hematopoietic stem and progenitor cells, @PKU1898 scientists discovered that BRAF inhibitors could effectively promote progenitor cell proliferation by temporarily delaying #erythroid differentiation.
π https://t.co/aFLJWPVlmz

π A review about #erythroid progenitor cells (EPCs) in cancer.
Scientists from Wuhan University summarize the latest advances in EPCs and cancer, paving the way for an in-depth discussion of how EPCs regulate cancer immunity in the subsequent sections.
https://t.co/OahAqGUw2x

Vimentin expression diminished during normal erythropoiesis in CD34+ cord blood cells, whereas it persisted in #erythroid cells differentiated from human ESCs, reports a Beijing Institute of Radiation Medicine team.
π https://t.co/oDYbhrxbCU

Discover murine π models of #erythroid 5ALA synthesis disorders in @BloodJournal study!
Dr. @SarahDucamp's team describes the phenotypes of mouse models of X-linked Sideroblastic Anemia, the SLC25A38 #anemia, and X-linked Protoporphyria. @harvardmed
π https://t.co/s6SYOKSwq0

Finding the co-regulators in #erythroid and #myeloid differentiation can help to find new target for therapy of AML.
Researchers show that Ξ±-lipoic acid targets π― ELK1 to balance human neutrophil and #erythrocyte differentiation.
π‘ Learn more: https://t.co/w2kq5jk82W

A case with distinct bone marrow findings associated with a noncanonical UBA1 variant - @AshKishtagari
https://t.co/hwGN1khtyY
#BoneMarrow #Cancer #Erythroid #OncoDaily #Oncology

Experiments detailed in @CR_AACR demonstrated that #erythroid differentiation enhanced RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts.
π https://t.co/OKT6Zwnmba

Dr. Laurie Steiner and the team at @URMC_DeptMed identified a key role for HEXIM1 in controlling π©Έ #erythroid gene expression and function, with overexpression of HEXIM1 promoting erythroid proliferation and fetal #globin expression.
@BloodJournal | https://t.co/GXxkzZf5Ca

π An excellent resource for those of you interested in #immunotherapies for #hepatoblastomas!
π Check out the potential benefits of #immune evasion mechanisms and #erythroid cells as therapeutic targets!
πΆ As the most common #pediatric liver malignancy, #hepatoblastoma requires more effective therapies to prevent progression and lifelong impact.
#Immune evasion mechanisms via intratumoral #erythroblastic islands ποΈ may be the solution.
@CellRepMed | π https://t.co/FskA5dQUh5

The NFIA-ETO2 fusion blocks #Erythroid maturation and induces pure #ErythroidLeukemia in cooperation with mutant #TP53π
https://t.co/3QUsYUMf5r
@ASH_hematology @Maria_RieraP #PEL

#Rnh1 knockout in mice is embryonically lethal, shows #erythroid differentiation defects and #anemia phenotype. The #loss-of-function mutations in the human #RNH1 gene affects brain, muscles, eyes and cause infection-induced #psychomotordeterioration, #seizures, and #macrocyticanemia.
#Phenomics @ejhg_journal
https://t.co/IFkRXGMcRY

Scientists suggest that CD169-CD43 interaction might be a promising therapeutic π target for #erythroid disorders.
π Learn more about the role of CD169 in erythroblastic islands under #erythropoiesis!
@Haematologica | https://t.co/4vBfLOx2nu

Dr. Juerg Schwaller and the team at @UniBasel_en find that the NFIA-ETO2 fusion blocks #erythroid maturation and induces pure erythroid #leukemia π in cooperation with mutant TP53.
π More at @BloodJournal | https://t.co/bdwOm5jqhh

#Erythropoiesis is the process of making red blood cells, which when disrupted can lead to #anemia. Learn how the Leukemia-associated transcription factor #mllt3 is important for primitive #erythroid development during #zebrafish embryogenesis https://t.co/EygGjC6Wha

π’ New in @SciReports!
Using timelapse imaging, researchers led by Dr. Diane Krause (@dskrausemdphd) at @YaleMed have explored the #kinetics of megakaryocytic #erythroid progenitor clonal expansion and differentiation.
Learn more: https://t.co/Jq73xsWFFG

An exciting new study has been published in @SciReports!
Researchers at @OffCMCVellore developed #erythroid lineage-specific lentiviral RNAi vectors β suitable for molecular functional studies and therapeutic applications.
Learn more: https://t.co/pXK4npluT9

π¬Publication - by Dr. Sheng-Wei Lin, Steven Lin, Ching-Jin Chang @MDPIOpenAccess
This study demonstrates the regulatory network of #TRIM28-mediated #cellgrowth and #erythroid #differentiation in #K562 #leukemia cells. https://t.co/prKGQ0HFiT
#biochem #biochemistry #knockout
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