Top Tweets for #FindMySequence
An approach used to detect sequence-register shifts in cryo-EM models of proteins can also be used to detect register shifts in crystal structure models, and five examples are described #MacromolecularCrystallography #RegisterShifts #FindMySequence https://t.co/ISXjQtJ8Xc
@WolframSeifertD @ChavesSanjuan @ImagingArtifact You can try Omokage search https://t.co/OJUCPVfCWq
fit #AlphaFold predictions of top hits and try to confirm their sequences with #findMySequence. @3Dstructure and I got pretty good results using this approach at resolutions better than 5A. Your resolution seems lower though.
Grzegorz Chojnowski: Sequence-assignment validation in protein crystal structure models with checkMySequence @ActaCrystD @IUCr #MacromolecularCrystallography #RegisterShifts #FindMySequence https://t.co/ISXjQtJ8Xc
@SjorsScheres very nice work! btw, #findMySequence already uses #HMM profiles for the sequence identification and assignment (not the highest probability amino acids as you wrote in the preprint). eager to see how it performs with backbone traces from your tool :)
EMBL Hamburg researchers & collaborators have identified an unknown protein in snake venom, using a software called ‘findMySequence’.
The new software identifies a protein’s amino acid sequence based on cryo-EM and X-ray crystallography data.
https://t.co/oOSja3Aw05
(7/10) We teamed up with @EMBLHamburg @ktototak who developed the amazing #Findmysequence, and we made a protocol to solve our cryo-EM maps from cell extracts using @DeepMind #Alphafold models from #CollabFold, resolving the ambiguous keto-acid dehydrogenase core!
(7/10) We teamed up with @EMBLHamburg @ktototak who developed the amazing #Findmysequence, and we made a protocol to solve our cryo-EM maps from cell extracts using @DeepMind #Alphafold models from #CollabFold, resolving the ambiguous keto-acid dehydrogenase core!
#checkMySequence is a comprehensive protein-model sequence validation tool for #cryoEM. I will talk more about it at tomorrow’s @ccp4_mx #CCP4SW session. Including results with that are not in the preprint, stay tuned!
@EMBLHamburg @embl #findMySequence @gitlab
Sequence assignment validation in cryo-EM models with checkMySequence https://t.co/UEXzGkh38N
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