Top Tweets for #GLUT2

over 1 year ago

Excited to share that our new study has been just published in @MolMetab . In this work, we uncover an unexpected role for kidney #GLUT2 in regulating whole-body energy metabolism under non-diabetic conditions. By selectively deleting GLUT2 in kidney proximal tubule cells, we disrupted glucose reabsorption and observed a systemic metabolic shift: increased food intake, enhanced carbohydrate oxidation, greater fat and lean mass, and a significantly improved lipid profile. These systemic changes were driven by renal metabolic reprogramming, including elevated #taurine and #creatine reabsorption, overactivation of #mTORC1 signaling, and increased #endocannabinoid tone. This study challenges the conventional view of the kidney as a passive glucose filter and highlights its active role in maintaining energy homeostasis. A heartfelt thank you to @MajdoleenAhmad, a great PhD student, and to Dr. @LiadHinden, for leading this project with impressive depth and scientific insight. Your hard work and commitment brought this study to life. #MolecularMetabolism #GLUT2 #MetabolicReprogramming #EndocannabinoidSystem #EnergyHomeostasis #TheTamLab Metabolic Consequences of Altered Kidney Glucose Reabsorption under No... https://t.co/RXIeShq5hC

923

Sable Systems Int'l @SableSysInt

over 1 year ago

How does glucose transporter 2 (#GLUT2) in #kidney contribute to regulating cellular & systemic #EnergyMetabolism? With help from Promethion #Metabolic Cages, scientists assessed the impact of targeted removal of GLUT2 from kidney proximal tubule cells. https://t.co/GDTihopAAi

235

Top Tweets for #GLUT2

Last Seen Hashtags on Sotwe

Trends for you

Most Popular Users