Top Tweets for #Gpx4
GPX4-targeting therapy reduces epigenetic age markers and circulating inflammation, raising questions about effects beyond treated skin.
https://t.co/mo8yIIswhN
#longevity #geroscience #GPX4 #epigeneticage #inflammation
#ToDieOrNotToDie, that is the question! For #FerroptosisLovers & more! Chu &co show @CellCellPress that #glutathione does more than protecting from ferroptosis via #GPX4 but it is also fundamental for #FSP1-mediated protection! https://t.co/GuHXS89hGr
Looking for ways to overcome #ChemotherapyResistance?
This review explores how #ferroptosis targets #IronMetabolism, lipid peroxidation, and #GPX4 signaling to restore drug sensitivity in #DigestiveSystem #cancers.
#OpenAccess: https://t.co/qRV1eoMLnK
GPX4 is dispensable for brown fat thermogenesis in vivo.
Check new Research Article published from FOS, by Dr. Qian hu’s team and Prof. @fudi_wang.
🔗: https://t.co/kxS5KJhV6Y
#GPX4 #ferroptosis #research #science
🙌 hey #AACR26, how can we make mutant selective #PI3Kalpha inhibitors work even better? Stop by our poster Tuesday afternoon by @AACR travel award recipient @md_napolitano and Yuan Wang on targeting #GPX4 along with mutant PI3K to enhance sensitivity to #ferroptosis @utswcancer
Mountain View biotech’s lead GPX4 modulator, RLS-1496, has delivered positive preliminary Phase 1 results in first human trial of a GPX4 modulator.
https://t.co/QmGXbyD2Bo
#longevity #geroscience #gpx4 #clinicaltrials #biotech
@LifeRubedo
📰New & Featured | Cell: #GPX4 released during #ferroptosis binds to dendritic #ZP3, activating cAMP-PPKA signaling
🔸Inhibits #glycolysis
🔸Impairs DC maturation & activation
🔸Eventually results in T cell priming defect
🧐Blocking GPX4-ZP3 potentially drives #antitumor activity
🧬A Cell study found that the #GPX4 p.R152H mutation makes neurons prone to lipid peroxidation, triggering #Alzheimer’s-like pathology and highlighting #ferroptosis as a potential therapeutic target in #neurodegeneration. Discover the full study here: https://t.co/e8YlniwJlP
Article✍️#KRAS #mutant #colon #cancer-targeted induction of #ferroptosis via #photocatalytic activation of #BiVO4-embedded silica nano with cascadic downregulation of #GPX4/#xCT axis. From Dr. Yang @InhaUniversityCollegeofMedicine;
https://t.co/VkdzFPgQhm.
Congrats to Tyson Sharp and his colleagues on the bioRxiv paper on LIMD1 loss conferring #GPX4 sensitivity in lung cancer. An important #cancer #ferroptosis study.
https://t.co/9HrCs57TuH
Here is our latest paper in @ACSBiol on compounds that restore activity to the R152H #GPX4 variant, found in patients with SSMD. Congrats to Hengrui, Farhad and Russ on a great collaboration! @columbia #ferroptosis https://t.co/BBGYrcvAWl
New paper of @GotteProf @uni_muenster & #IBYME #CONICET: #Ferroptosis regulators in #Endometriosis: https://t.co/D8itRDgp3O Congratulations to @MSCActions @TRENDO_EU secondee Lidia Mielke @UK_Muenster! @REA_research #endometriose @DG_Endo @DGGG_eV @EuroEndoLeague #GPX4 @DGGEF7
📖Start your week with a Review!
A guide to ferroptosis in cancer
🔓https://t.co/EGlbTmxOD0
🖋️@vonKarstedtLab
#Ferroptosis #CancerBiology #CancerMetabolism #CancerInflammation #GPX4
Here are thoughts on our new paper published today in @CellChemBiol on targeting #GPX4 to induce #ferroptosis -- link to free download available there. Congrats to the team & Enjoy! @columbia @Columbia_Bio #cancer #biochemistry https://t.co/EAB6K3E6Vj
Article✍️Targeting a novel inducible #GPX4 alternative isoform to alleviate #ferroptosis and treat metabolic-associated #fatty #liver disease.
https://t.co/WsYSshKw6Y
💡#Issue 9, Online Now!🎀 Cover Story🎀Authors' findings have illustrated a previously-unknown role of #GPX4 alternative isoforms switch in #ferroptosis regulation in #MAFLD progression and should shed a light on the prevention and treatment of MAFLD.
https://t.co/7AMyqQHhO2
Abstracts for #CSHAsia meeting on #Iron, #ROS & #Ferroptosis in Life, Death & Disease is due this Friday Aug 12. Please submit in time via https://t.co/jgmDdwXoms
N.B. Registration remains open until before meeting starts
#Redox #Celldeath #lipidperoxides #Cancers #GPX4
The final abstract deadline for #CSHAsia meeting on #Iron, #ROS & #Ferroptosis in Life, Death & Disease https://t.co/eoB4B3qQpB is extended to Aug 12, 2022. Please note that registration remains open until before meeting starts.
#Redox #Celldeath #lipidperoxides #Cancers #GPX4
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