Top Tweets for #HC010
🇨🇳 #Hongcheng BioPharma has registered a PD-1/CTLA-4/VEGF tri-specific antibody #HC010 on the NMPA’s Platform, it is a multicenter, single-arm, open-label Phase II clinical trial as 1L PD-L1-positive advanced NSCLC treatment.
The enrollment criteria is PD-L1-positive (TPS ≥1%), EGFR-negative, ALK-negative locally advanced or metastatic NSCLC. Plan to enroll 50 patients.
The dose is 15 mg/kg, the same as PD-1/VEGF bispecific antibody ivonescimab developed by Akeso.
HC010 enter Phase 1 study in February 2024.
HC010 is designed with a symmetrical structure, linking the scFv of PD-1 with a VEGF monoclonal antibody and a CTLA-4 nanobody in series.
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Leggi l'articolo @_ChannelTech
https://t.co/oUnAvL3qYP
#AvayaVantageK155 #DaaS #Devices #Cloud #UCC #remoteworking #B129 #HC010 #ExperiencesThatMatter #AvayaSpaces

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