Top Tweets for #HCVCure
Happy to share our publication on a single-cell atlas of human liver immune (myeloid) cells in #HCVCure in the @JHepatology !
A tribute to one of the most remarkable medical breakthroughs of modern times: the #HCVCure. Since the introduction of direct-acting antivirals in 2011, hepatitis C virus (#HCV) infection has become the first chronic viral infection to be curable, with newer generation antivirals achieving a >95% success rate within just 8-12 weeks of treatment.
What lessons can we learn from this success?
Paper: https://t.co/uEYvI2EEAO
Editorial: https://t.co/pT6s39cwx5
As part of a Phase 3b open-label clinical trial, we used single-cell genomics to systematically profile myeloid cells in the livers of individuals with HCV before and after viral clearance. We identified cell populations with immunoregulatory potential during active infections: ISG-high neutrophils and eosinophils were found to upregulate PD-L1 and IDO1, respectively, and proliferating dendritic cells increased post-cure. Further, we identified a correlation between pre-treatment viral load and the post-cure host immune state. We hope the data will inspire the development of immunotherapeutic strategies for other infections that currently lack a cure.
Acknowledging our incredible team for making this work possible @nalatrak, #BoLi, @raychungmd, #NirHacohen, #MichaelWallace, #AnnaGonye, #ChrisOetheimer, #HaileyPatel, @PierreTonnerre, #GeorgLauer, and many others.
@broadinstitute @MGHMedicine @harvardmed #HCV #Liver #Infections #ImmuneCells #SingleCell #DirectActingAntivirals #DAAs
@elllebele @thecurbsiders @elllebele Love it! Exactly the intent! Please jump on the #HCVCure bandwagon...the more treaters the better
Don't miss your opportunity to register for #ILC2021 @EASLnews @EASLedu
Reason #1:
Hear from Charles M. Rice (@RiceLaboratory), Michael Houghton & Harvey J. Alter - 2020 Nobel Prize Laureates in Medicine in a "Meet the Experts session" #hepatitisC #HCVcure
June 23rd-26th
Don't miss this session at #ILC2021. An inspiration for basic #hepatology scientists.
🏆A live conversation with the 2020 #NobelPrize Laureates in Medicine.
➡️Register now on https://t.co/x7uFDwD2MJ
@EASLedu @JHepatology @EASL_ilf
This happens at least once a week. It’s past time to do away with #priorauths and other barriers to #treatmentaccess for #HCVCure
Pamela Belperio, PharmD talks about #HCV treatment at the #VA- they have cured 100,000 people!!
Amazing that 65% of cures were initiated by #Pharmacists, #NursePractitioners & #PhysicianAssistants!
@altVAHealth @ASTHO #NOhep #HCVCure #PrimaryCare
#HealthForAll Taiwan has removed all restrictions on latest #DAA for #HCVCure. Starting June 1 all patients regardless of infection period, fibrosis stage, all are eligible for National Health Insurance coverage using pan-genotypic Maviret or Epclusa.
https://t.co/bcwbWifUS7
#HCVcure is available for HCV, but we need infrastructure, outreach, testing, linkage to care, access to affordable meds, follow-up. Need to empower most-affected people with disparate access to care. https://t.co/LjPbUEaUjX
A surgeons life saved by a heart from someone with #HepC. Great story about how #HepC curative therapy is changing the availability of organs for lifesaving transplants! Access to #HCV meds is crucial! #TheDoctorPatient #NOhep #HepatitisElimination #HCVCure @aasld
@Hep_Alliance
When the doctor becomes the patient: The head of NYU's transplant program received a heart transplant from a drug user with hepatitis C, an increasingly common practice that is revolutionizing the transplant landscape. My story: https://t.co/GC7SHNnZYx via @WSJ
@SeragHashem Welcome to Miami! Looks like an all-star lineup for @AASLDtweets in Feb 2019. Great chance to hear the @BCMDeptMedicine boss speak on national stage about #HCVCure @hcvresearchnews @AmerGastroAssn @DDWMeeting
I could watch this all day 😍
Its all teamwork to #EliminateHepatitis. At @SaintBarnabasNJ,
a clinical pharmacist & a patient navigator work closely to link #HBV #HCV patients from the #EmergencyDepartment to an outpatient practice for #Treatment & #HCVCure to prevent #LiverCancer! #WorldHepatitisDay #NOhep
Let’s Talk About It: Transhealth - Join the us on August 14th @ 10am FacebookLive and @ 10:15am InstagramLive! Stay up-to-date with #CEI monthly series! Topics include: #hiv #std #hcvcure #ete2020 #HIVAIDS #publichealth #NYSAIDSInstitute @HealthNYGov ... https://t.co/8vzR4vWCiF
Barriers to treating #children with #HCV. Children are being left behind #HCVcure #hepatitis #hepC https://t.co/eD7MWYfH8I
#sweetlittleboy #hugsandkisses #hcvcure #hcvtreatment #sofosbuvir #sovaldi #daklinza #migraine… https://t.co/YCwbYlOtKS
#Abbvie #Viekira Licensed in UK http://t.co/gLVVRdzESi #hcv #hepc #hepaware #hepatitis #hepatitisc #hcvcure #liver14 #aasld2014 #aasld14
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