Top Tweets for #HeliosB
El Simposio HELIOS-B cierra la jornada del #59CongresoSAC fuera del Palacio de Congresos.
Los Dres. García Pinilla y Urbano Moral, dos de los mayores expertos en ATTR-CM de Andalucía, a debate sobre vutrisiran moderados por el Dr. Recio Mayoral.
#SAC26 #ATTRCM #HELIOSB
@EJHFEiC
What impact does vutrisiran have on physical function and quality of life in patients with #ATTRCM? #HELIOSB
Read more 👉 https://t.co/lrr1yMAAi5
#HeartFailure #Amyloidosis
📉 Earlier is better: Vutrisiran works across ATTR-CM stages, but the biggest survival gains come in early disease. Time is myocardium. https://t.co/g15HnWI5c7
#JACC #HELIOSB #ATTRCM #Vutrisiran #Amyloidosis @MathewMaurer @Ron_Witteles
#HeartFailure2025 #LBCT by @MariannaFonta11
#HELIOSB Recently FDA approved Vutrisiran RNAi therapeutic reduces mortality through 42 months in #ATTRCM
#MedIQHF2025
💥 #ATTR-CM treatment isn’t one-size-fits-all anymore. #JACC’s latest review breaks down how #FDA-approved therapies and next-gen agents are reshaping the field. https://t.co/Lu7EUpwEgH
#Amyloidosis #HELIOSB #Tafamidis #Vutrisiran #Acoramidis @ktkadakia @hmkyale @MKIttlesonMD
In these prespecified & post hoc analyses of data from the phase III #HELIOSB trial in pts w/ #ATTR-CM, #vutrisiran consistently 📉 risk of all-cause & CV mortality, & rates of CV & HF 🏥 & urgent HF visits vs placebo https://t.co/dp7H3h3g5J
#Heartfailure2025 #JACC @Ron_Witteles
#HeartFailure2025 #LBCT by @MariannaFonta11
#HELIOSB Recently FDA approved Vutrisiran RNAi therapeutic reduces mortality through 42 months in #ATTRCM
#MedIQHF2025
RNA interference therapy Vutrisiran shows MORTALITY REDUCTION in ATTR amyloid cardiomyopathy (HELIOS-B trial)! 💥
🔗 https://t.co/NQFKh54WuO
#CardiacAnesthesia #Amyloidosis #HeartFailure #RNAtherapy #HELIOSB #JCVA
#AHA24 ICYMI: #JACC AE Dr. @MKIttlesonMD & Dr. @MariannaFonta11 discuss the #HELIOSB trial examining worsening outpatient #heartfailure among patients with transthyretin #amyloidosis with cardiomyopathy.
📄: https://t.co/9aLv5VR98E
#AHA24: In #JACC, Drs. @MariannaFonta11, @MathewMaurer, @scottdsolomon, et al present a secondary analysis of the #HELIOSB trial, showing that vutrisiran significantly reduced the risk of outpatient worsening HF in pts w/ #ATTR-CM https://t.co/9aLv5VR98E
More data from #HeliosB on NTproBNP and troponin presented #HFSA2024 - vutrisiran vs placebo on the background of tafamidis in 40% at baseline and another 10% drop in during the trial.
Consistent effect across all subgroups, including those on baseline tafamidis
#CardioTwitter
Great LBCT session this AM @HFSA #ASM2024 with high impact data from #STEPHFpEF, #FINEARTS, and #HELIOSB and a number of simultaneous publications. Looking forward to another amazing LBCT session tomorrow!
🔥#HeliosB results #Vutrisiran @Ron_Witteles @MyASNC
🙌#cardiacAmyloidosis
🌟Favorable impact on multiple measures of disease progression
➡️Combination with #Tafamidis
❤️Reduce all cause of mortality 🌟 #Amyloidosis
🔥#HeliosB results #Vutrisiran @Ron_Witteles @MyASNC
🙌#Amyloidosis
❤️ Great results at primary and secondary results
🔥#HeliosB results #Vutrisiran @Ron_Witteles @MyASNC
➡️Great news for #Amyloidosis patients 👏👏👏
❤️ Study design
#HeliosB
#ESCCongress
#Friday #Hotline
🍩 patients with ATTR-CM, 💊 with vutrisiran led to a ⬇️ risk of death from any cause and cardiovascular events than placebo and ↔️preserved functional capacity and quality of life.
Beautiful infographic @escardio
🔗 https://t.co/JlWP38Zg4b
#StopOrNot
#ESCCongress
#Friday #Hotline
➡️discontinuation of a renin-angiotensin system inhibitor (RASI) before non-cardiac surgery resulted in a similar rate of major post-operative complications compared with RASI continuation.
➡️Rates of hypotension during non-cardiac surgery were higher and longer in the continuation group but this did not translate into a higher risk of post-operative complications.
➡️Given the similar rate of post-operative complications, the choice of continuation/discontinuation could be made based on individual patient needs.
🔗 https://t.co/ipgpFjSu3r
@mirvatalasnag @DBelardoMD @HeartOTXHeartMD @DrToniyaSingh
Remarkable results in phase 3 study with vutrisiran in patients with ATTR-CM
"The study met all the 10 endpoints", says Marianna Fontana. Watch: https://t.co/VE87nx1f3s
#ESCCongress #vutrisiran #cardiomyopathy #ATTRCM #HELIOSB #ATTRamyloidosis #CardioTwitter
Schönes Beispiel dafür, dass die Börse mit Fantasien handelt. Unten (li) der @Alnylam Aktienkurs. Der Riesensprung im Juni war die Verkündigung der Topline Ergebnisse der #HeliosB Studie per Pressemeldung. Heute bei #ESCCongress2024 in London wurden Details vorgestellt (re) (1/2)
Another game changer just revealed at the #ESCcongress 2024 !
#HELIOSB reached his primary endpoint!
@escardio
Exciting Results from #HELIOS_B Trial! 🌟
📍Double-blind, randomized
📍#Vutrisiran in #hereditary or wt #ATTR_CM
📍655 px, mostly elderly males with NYHA FCII
📍#Vutrisiran 25 mg vs. placebo q3 mo, plus #tafamidis if ongoing
🎯 Results:
📍Primary Endpoint: Significant ⬇️ in all-cause mortality & #CVevents by 28% overall
📍Secondary Endpoint: Marked ⬇️ in all-cause mortality by 36% overall, 35% in monotherapy group over 42 months
📍Notable⬆️ in FC, QOL, and NYHA class
#ESCCongress @ThibaudDamy
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