Top Tweets for #IOBridge2021
#IOBridge2021 | A comment of @PAscierto about digital solution for optimizing the management of melanoma patients.
@FunchainMD @BernardAFox @ProfGLongMIA @jasonlukemd
A brief comment of Igor Puzanov about his debate at #IOBridge2021
@OmidHamidMD @FunchainMD @ProfGLongMIA @jasonlukemd @PAscierto
Rapid process to accelerate turn around 4 multiplex IF/IHC/#FoxLab got a @lunaphore last month/If reproducible it would have advantages 4 staining 1 slide or 4 slides with comet unit #IOBridge2021 #JEDIcouncil #immunoscore @AkoyaBio @NeoGenomics @Ultivue @LeicaMicro @ventana
Amazing session on #neoadjuvant #immunotherapy covering many cancer types/Great discussion on similarities and differences in biomarkers & response/opportunity for innovation/small studies & can get deep in science/ list of speakers below. @PAscierto @FondMelanoma #IOBridge2021
Another Great Debate/ #intralesional therapy:Oncolytic Virus versus other specific immune modulators? Profs Igor Puzanov @RoswellPark & @OmidHamidMD @angelesclinic /Attendees shifted towards other modulators in future @PAscierto @FondMelanoma #IOBridge2021
Another GREAT DEBATE! Can #Cancer #Vaccines turn a cold tumor hot? Profs. Lisa Butterfield @parkerici & Olivera Finn @UPMCHillmanCC Argue point/Prof Butterfield is yes/Prof Finn is MAYBE/depends on right Ag/Great discussion #immunotherapy @PAscierto @FondMelanoma #IOBridge2021
2) Prof @PAscierto #immunotherapy Guru @istitutotumori @FondMelanoma talks real world data anti-PD1 4 cutaneous squamous cell CA (#CSCC) / more data immunotherapy works in older population 80-93 y/o /lots of examples #cemiplimab /before PD1 these pts had no chance/#IOBridge2021
1) Prof @PAscierto #immunotherapy Guru @istitutotumori @FondMelanoma talks real world data anti-PD1 4 cutaneous squamous cell CA (#CSCC) / more data immunotherapy works in older population 80-93 y/o /lots of examples #cemiplimab /before PD1 these pts had no chance/#IOBridge2021
Prof Dirk Schadendorf #skin #cancer expert @UniklinikEssen provides perspective on aging European population/it will have increased incidence of non-#melanoma skin cancers/discusses targeted #HHI & #immunotherapy/responses in >70 y/o @FondMelanoma #IOBridge2021 @PAscierto
Prof Inge Marie Svane Director @CCITdk gives AMAZING talk about her #iDO #cancer #vaccine + anti-PD-1 showing high ORR in patients with #melanoma / more hints that vaccines with self antigens and #CPI could benefit pts @FondMelanoma #IOBridge2021 @PAscierto @ubivac @Incyte
1) Prof Luigi Buonaguro #HCC #vaccine expert at @istitutotumori describes HCC vaccine design & clinical trial/hypothesizes incr TCR diversity, induced by viral inf assoc with anti-cancer immunity & protection useful 2 develop potent vaccine @FondMelanoma #IOBridge2021 @PAscierto
Wonderful talk by Prof Sandra Demaria from @WeillCornell showing recently published work in #JCI on the power of RT-modulated tumor antigenicity @FondMelanoma #IOBridge2021 @PAscierto
Prof. Sandra Demaria #tumor #immunology / #radiation Expert @WeillCornell presents data showing how Radiation increases expression of antigens, MHC I & II, & death receptors sensitizing tumor to immune response/lots of unpublished data @FondMelanoma #IOBridge2021 @PAscierto
Prof @carlobifulco #molecular #pathology ROCKSTAR @ChilesResearch @providence AMAZING! Describes work with @Microsoft & ODA 2 build virtual molecular #tumor board & underscores how critical it is 2 delivery of optimal #cancer treatment @FondMelanoma #IOBridge2021 @PAscierto
Exceptional talk by Prof Carlo Bifulco @carlobifulco on the virtual molecular tumor board as a tool for delivery of precision oncology. AI being applied in medicine too. @FondMelanoma #IOBridge2021 @PAscierto @BernardAFox
Prof Janis Taube #multiplex IF & pathology Guru @HopkinsMedicine provides unpublished data & novel insights into #cancer patients most likely to respond to #immunotherapy/will be future to determine pt tx @AkoyaBio @Ultivue @NeoGenomics @FondMelanoma #IOBridge2021 @PAscierto
Prof @JeromeGalon #IMMUNOSCORE ROCKSTAR @Univ_Paris #INSERM reviews importance of identifying immune infiltrates in cancer & reports high immunoscore in #rectal cancer may identify patients that don’t require surgery/reports no recurrence @FondMelanoma #IOBridge2021 @PAscierto
The 2nd Great Debate! Do early surrogates correlate with long-term survival? Profs. Michael Postow @ #MSKCC & Jeffrey Sosman @NUFeinbergMed/Clinical markers outweigh biomarkers/my opinion-We need validation of mIF #JEDIcouncil @FondMelanoma #IOBridge2021 @sitcancer @PAscierto
Thanks for the invite! It was an honor. I definitely had the harder side! Either way, let’s target those B cells. #IOBridge2021
The GREAT DEBATES have started! 1st debate is btwn @fridmanwh & @BcellBruno to debate whether B cells have a therapeutic role in the response to #cancer #immunotherapy/ Starting with 100% pro - Prof. Fridman is hoping to get to 200% pro/ @FondMelanoma #IOBridge2021 @PAscierto
The GREAT DEBATES have started! 1st debate is btwn @fridmanwh & @BcellBruno to debate whether B cells have a therapeutic role in the response to #cancer #immunotherapy/ Starting with 100% pro - Prof. Fridman is hoping to get to 200% pro/ @FondMelanoma #IOBridge2021 @PAscierto
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