Top Tweets for #LabInvestigations
Antimicrobial Resistance has increased over time in Uganda, this is probably due to #SelfMedication. While @guguddetvuganda we discussed why #LabInvestigations are very relevant to proper diagnosis and proper treatment.
Every Ugandan, is urged to ensure actual diagnosis before any treatment given.
#HealthProgram | #AMResistance.
@eddympuuga @MinofHealthUG @johnpmcdermott @BarbaraNyamwiza @Nkwanga_Michael @Microhaem @JaneRuth_Aceng

Read "Antimicrobial resistance trends in clinical Escherichia coli and Klebsiella pneumoniae in Ethiopia"
Download https://t.co/YkoYHy3vhO AOSIS Publishing @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
Read "Fosfomycin susceptibility testing and resistance mechanisms in Enterobacterales in South Africa"
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Read "Genomic analysis of KEL*03 and KEL*04 alleles among Thai blood donors"
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Read "Sentinel laboratory compliance with best practices in Burkina Faso’s antimicrobial resistance surveillance network"
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Read "Fighting cervical cancer in Africa: Taking a closer look at human papillomavirus 35"
Download https://t.co/0I8VFXHQwE Sophia U. Okeke @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
Read "Acknowledgement to reviewers"
Download https://t.co/d81Vskbhkc Editoial Office @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
Read "Critical values notification: A nationwide survey of practices among clinical laboratories across Nigeria"
Download https://t.co/Pa0Qnp67ts AOSIS Publishing @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
18th July @guguddetvuganda discussed #LabInvestigations with @jcrc_official1 Specialist Mr Benson.
It is not ethical to detect to the clinician the tests you wish to be done. Clinicians are trained and are competent to assess your situations and request for tests he/she thinks will be beneficial to your health. But today due to the Internet and social media, each is a clinician in his/her own wisdom.
This may have dare consequences in terms of cost, creating anxiety, and many other negative effects. Because you may fail to help yourself after receiving the negative or unanticipated results.
Way forward;
Let us use for travel, or prognosis).
Laboratory investigations are relevant because:
Each patient, researcher, traveller, or a Doctor, desire to have a quality result.
A quality result must have the following attributes:
Reproducible, reliable, and timely
If any of the above falls short, then that result has not met the purpose
The list of lab tests done at JCRC is many.
We have several departs in the lab, and each depart has specialized tests using STATE-of-ART Equipment.
We also have BSL 3 labs to handle any infectious disease that may occur in the country
One of these labs we use it for TB tests Cultures. Other TB tests are (microscopy, GeneXpert). We also do HPV screening to rule of cervical cancer in women
Chemistry: LFT (Albumen, T. Protein, bilirubin, ALT, AST ALP etc); RFT (Urea, electrolytes, Creatinine etc); Glucose, Glycerated haemoglobin (HBA1C); and PSA in men; Automated Hepatitis B and C screening, Toxoplasma, CMV etc
Because we are starting BMT, we are introducing tests for monitoring certain drugs in the patient; Cyclosporin and tacrolimus.
Hematology: CBC, Malaria, ESR, Sickle cell genotype; Coagulation tests (Thrombin time, prothrombin time, INR, Factors VII & IX etc); ABO blood grouping & Screen for antibodies, and Cross match.
Immunology: HIV screening, HIV confirmatory tests, CD4/CD8, TB QuantiFERON, and other research tests
Microbiology: Blood culture for bacteria and fungi, swabs collected from different body parts, urine culture and urinalysis, microscopy, Syphilis testing, etc.
Molecular Biology:
HIV RNA viral loads, Hepatitis B & C viral loads, STI (Neisseria gonorrhoea, Trichomonas vaginalis, Chlamydia trachomatis)
HIV Drug resistance testing. Other research assays.
Indications for lab tests: This is usually determined by the clinician who has access to the patient. He/she interacts with the patients and comes up with a request form for lab tests or any other tests outside the lab.
How do you maintain quality?
This is a very expensive investment that an institution that cherishes the quality of the lab results will have to be undertaken. Is not an option!
In the lab, we have a quality management system (QMS) built on 12 pillars, but I will mention a few;
Staff, Infrastructure, Quality Equipment & validate or verified, Good supply of reagents/controls, External Quality Assurance scheme(s), Internal audits, Safety of staff and surroundings, Internal controls, Lab Information management system (LIMS)
JCRC Laboratories (Lubowa) are accredited by the USA College of American pathologists (CAP) since 2017 to date, with inspections after every 2 years
JCRC Laboratory in Mbarara Hospital is accredited by the South Africa national Accreditation Scheme (SANAS).
This FY, we are embarking on preparing Fort Portal Lab for accreditation, then Gulu like that…
ii. diagnosis?
Accurate diagnosis heavily relies on lab tests and other diagnostic tools.
But this journey has yielded good results, and now Uganda lab is divided into 3 main components:
Pre-examination: phlebotomy, collections of samples, account for over 70% of the diagnosis of a patient. So, lack of or poor lab results may lead to poor patient outcomes from his/her sickness.
Uganda and Health Lab service delivery:
As a country, we embarked on the accreditation process of public and not-for-profit lab way around 2010.

Read "Effect of delayed sample draw after blood collection for haemoglobin test in South Korea"
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Read "Using the SLIPTA checklist to assess laboratory readiness for Joint Commission International accreditation"
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Read "Antimicrobial susceptibility of bacterial uropathogens in a South African regional hospital"
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Read "Building clinical pharmacology laboratory capacity in low- and middle-income countries: Experience from Uganda"
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Read "Consequences of rpoB mutations missed by the GenoType MTBDRplus assay in a programmatic setting in South Africa"
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Read "The COVID-19 pandemic in sub-Saharan Africa: The significance of presumed immune sufficiency"
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Read "Medical laboratory practice in Malawi – Current status"
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Read "Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa"
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Read "Acknowledgement to Reviewers"
Download https://t.co/CfjRmUXKpU Editoial Office @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
Read "Point-of-care testing: Connecting communities in Africa and ensuring equity in access to health and diagnostics"
Download https://t.co/nz9tUWaD3p Rajiv T. Erasmus @_AOSIS @ASLM_News #LabKnowledge #LabSystems #LabPolicies #LabInvestigations
Read "Impact of rapid centrifugation on routine coagulation assays in South Africa"
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