Top Tweets for #MiamiHeartStudy
Big appreciation for @BudoffMd @JonFialkowMD @realDaveFeldman @khurramn1 et al. giving us in #cvPrev lots of ponder/discuss this weekend at WCIRDC with their #LMHRstudy KETO Study presentation. Looking fwd to reading the full publication & follow-up results. #MiamiHeartStudy
And if I can take a moment to emphatically thank YOU, @khurramn1 🙏🙏🙏
Had you and your team not have initiated the #MiamiHeartStudy, we'd have no sizable comparison dataset to gather metabolically healthy, matched controls.
Delighted that #MiamiHeartStudy @BaptistHealthSF could contribute to this critical issue. Next step is prospective follow up for changes.
@JonFialkowMD
Delighted that #MiamiHeartStudy @BaptistHealthSF could contribute to this critical issue. Next step is prospective follow up for changes.
@JonFialkowMD
🚨🚨🚨🚨🚨🚨🚨🚨
BREAKING: @BudoffMd has now presented the matched analysis for:
KETO (#LMHRstudy) vs Control (#MiHeart)
-🙏Please RT🙏-
METHODS – 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS – High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
🚨 There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
🚨 There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
🚨 No relationship of LDL-C elevations and plaque
⚠️ This analysis is on baseline scans and the study is still ongoing for second CCTA completion in our cohort by February of 2024. And as always, please continue to work with your doctor.
- I will have my own video reaction and thoughts in the coming hours.
🙏🙏🙏 to everyone -- and I mean everyone -- who helped us get to this pivotal milestone. 🙏🙏🙏
Had an amazing time at #ACC2023 #Day2 presenting our work from #MESA and #MiamiHeartStudy. Grateful to have such excellent mentors
@NCH_Heart
@HarborUCLA @RCubedduMD @md_viviana @BudoffMd @malbag1 @PU84 @lauramullerMD @sierrajuangui @DonmehlhornDO @SankalpPatelDO
@cury_ricardo ongoing major contributions to cardiac CT #MiamiHeartStudy #CadRads
@Heart_SCCT @BaptistHealthSF @jazdoctor @JonFialkowMD @HMethodistCV
while proud of unique #MiamiHeartStudy potential to unravel secrets of early CAD ,also believe @BaptistHealthSF setting example for other health systems to invest in their community, for creating R&D infrastructures
would @nih_nhlbi leverage these assets?
https://t.co/QVlD9tDVSx
@khurramn1 @Heart_SCCT @BaptistHealthSF @JackZiffer @DrBTKatzen @Calvinchb @drjbone1 @HMethodistMD @HMAIChief @WilliamZoghbi @hmkyale @cury_ricardo @CiccaroneCenter @rauldsf_santos @BudoffMd @RonBlankstein @MichaelJBlaha Congratulations @khurramn1 & Team on completing such an impactful study! Builds on SCAPIS & no doubt #MiamiHeartStudy will continue to inform for years to come.
@HarneetWalia1 @BaptistHealthSF @JackZiffer @DrBTKatzen @Calvinchb @drjbone1 @HMethodistMD @HMAIChief @WilliamZoghbi @hmkyale @cury_ricardo @CiccaroneCenter @rauldsf_santos @BudoffMd @RonBlankstein @MichaelJBlaha Thanks @HarneetWalia1
so delighted with your guidance and leadership on interplay of sleep apnea, cardiometabolic risk and early atherosclerosis.. so much to learn in #MiamiHeartStudy 🙏🙏
#3 What’s special about #MiamiHeartStudy
-Possibly only US population based cohort with insights on detailed coronary atherosclerotic plaque burden and features with extensive linkage to biomarkers/biobank, and other detailed data
Ongoing follow-up for events
#DiscoveryGoldmine
#2 Why need #MiamiHeartStudy?
As imprecise nature of risk factors becoming clear, evolving paradigm “see disease treat disease” with #CACScore, the next frontier is to further unravel mysteries of coronary atherosclerosis development & progression made possible by #CCTA
#1 Dreams do come true, needed a spark in 2014, health system @BaptistHealthSF inspired to make difference, bold leadership (@JackZiffer @DrBTKatzen @Calvinchb @drjbone1 & others), generous community coming together #MiamiHeartStudy to realize the first fruit of these efforts👇
#MiamiHeartStudy is drawing attention from experts worldwide. "We’re generating new knowledge that will change the way cardiovascular disease is perceived, managed and treated.” Learn more about the study at Miami Cardiac & Vascular Institute. #HeartMonth
https://t.co/gxr8UgKtMd
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