Top Tweets for #MyogenicResponse
Research Article by FB Hansen et al (@UsUlf @AarhusUni) Attenuated #myogenicresponse and #contractility in #middlecerebralarteries after #cardiacarrest: a randomized experimental #rat study
https://t.co/RQtqzJkRfu
After #LaserAblating pericytes around #PrecapillarySphincters, we observed impaired #MyogenicResponse and #NeurovascularCoupling—demonstrating #PrecapillarySphincter pericyte contractility is essential.
In aged mice, the #MyogenicResponse was significantly blunted. This was shown by an increased #CorrelationCoefficient (CC) between #VascularDiameter and #BloodPressure.
We challenged mice with acute #BloodPressure spikes (~70% increase via angiotensin II). Result: both adult and #old mice got their #MyogenicResponse and #NeurovascularCoupling disrupted.
Beautiful Ca2+ imaging of a #precapillarysphincter (Lower left side, at the #arteriole branch point) and capillary response to intraluminal pressure increase. #myogenicresponse #autoregulation
Here is a video of GCaMP expressing SMCs and proximal pericytes rapidly responding to pressure elevation. (We had to use serial z-stacks to accurately quantify vessel responses but single plane imaging is pretty!)
FREE Recommended Reading on #HeartFailure #SkeletalMuscle & #Exercise
#ExerciseTraining restores the myogenic response in skeletal muscle resistance arteries and corrects peripheral edema in rats with heart failure (Paula et al.)
🔓 https://t.co/ZUi9sNpqRd
#MyogenicResponse
Mechanotransduction in #gastrointestinal smooth muscle cells: Role of mechanosensitive ion channels (Joshi et al.) - new in AJP-GI
https://t.co/ZKZCfbAl2J
#ArticlesInPress #MyogenicResponse #Mechanosensation @beyderlab
#ArticlesInPress #EditorialFocus The role of transient receptor potential channels in cerebral myogenic autoregulation in hypertension and aging
https://t.co/TSnyPP46G9
#myogenicresponse #hypertension #aging #congnitivedecline
#ArticlesInPress Sex differences in the structure and function of rat middle cerebral arteries
https://t.co/MEY5zZK14L
@UMMCnews
#sexdifferences #distensibility #myogenicresponse #cerebralbloodflow #cognitivefunction
#ArticlesInPress Exercise training restores the myogenic response in skeletal muscle resistance arteries and corrects peripheral oedema in rats with heart failure https://t.co/RgEnRX4XDr
University of Sao Paulo
#exercise #myogenicresponse #heartfailure
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