Top Tweets for #NativeChemicalLigation
@AlannaSchepartz presented a fantastic seminar for the @UMN_BMBB Dagley lecture. I especially loved the elegant spin on #nativechemicalligation which I did a ton of in the Kent lab long ago! Was also HUH-gely fun to chat with her about #huhtags. #gordonlabpuns
“When you fall, get right back up. Just keep going, keep pushing it.” (Lindsay Vonn)
🕯 #LiCADV22
#PeptideScience #Peptides #BioactivePeptides #Proteins #Enzymes #NativeChemicalLigation
https://t.co/T7wQt0cWjr
“In my heart is a Christmas tree farm where the people would come to dance under sparkling lights …” (Taylor Swift, 2021)
🕯 #LiCADV22
#PeptideScience #Peptides #BioactivePeptides #Proteins #Enzymes #NativeChemicalLigation
https://t.co/T7wQt0uxaZ
🎁Do you recognize this PhD student in front of his hood in 1999? There he started out to become a true artist in @TotalSynthesis. Birthday present: autobio of S. Kent https://t.co/R1Nt95aCYZ, the artist of Total Synthesis of #Peptides/#Proteins & #NativeChemicalLigation. Cheers!
Our 1st 👣towards mirror-image monobodies🎊🎉 Synthetic L&D SH2 domain of a leukemia oncogene🎊Joint project with @hantschel_lab Sweet memories from my Postdoc at Seitz🙂 @RobZitterbart @TomNGrossmann Congrats Nina👩🔬&Frank👨🏼🔬 #NativeChemicalLigation @Uni_MR https://t.co/OiaExeDvUh
The Dawson Linker and its variants provide access to C-terminal peptide thioesters which are crucial components of Native Chemical Ligation reactions. Read on to discover all derivatives available at Iris Biotech!
https://t.co/XiX1DqzHCv
#DawsonLinker #NativeChemicalLigation
In #Peptide #Science: Synthesis of C‐terminal glycine‐rich o‐aminoanilide peptides without overacylation for use in benzotriazole‐mediated native chemical ligation by Fernando J. Ferrer‐Gago & Li Quan Ko
https://t.co/y4As3lmyVo
#chemistry #NativeChemicalLigation #synthesis
Protein chemical synthesis gives access to functional SUMO-2 and SUMO-3 #ubiquitin - like protein dimers. We used #NativeChemicalLigation and #SEAligation to produce these 21 kDa proteins at mg scale.
https://t.co/BlYJSEjZMb
Just accepted in @JOC_OL Naruse et al report the use of copper to cleave thiazolidines and selenozolidines and the utility in #NativeChemicalLigation strategies https://t.co/bpy9WYY3U8 #propepchem
Exploring the functional consequences of protein backbone alteration in #ubiquitin by #NativeChemicalLigation (Horne @Pitt_Chemistry) https://t.co/fHURd6wR2X
Congratulations @BengtGless. Very impressive PhD defense yesterday! The assessment committee was Kristian Strømgaard @UCPH_health , @ThomasBPoulsen from @AarhusUni , and @Dawson_Group of the @scrippsresearch #NativeChemicalLigation #AIPs #QS
A solubilizing trityl-type tag for #NativeChemicalLigation of Asx/Glx-containing peptides (Yoshiya at Peptide Institute, Osaka) #proteinsynthesis #protectinggroups https://t.co/bjl3oLjPVZ
An unusual observation of thioesters which don't react under #NativeChemicalLigation conditions. A cleavable backbone modification strategy was able to reverse this phenomenon @angew_chem https://t.co/t9rPHZVD6Q
William Seth Horne and colleagues (@Pitt_Chemistry) use #NativeChemicalLigation to create and explore #ubiquitin mimetics based on backbones that blend natural and artificial amino acids. Read more on @ChemistryViews https://t.co/sqTbLIpNAS.
Use of a #trityl solubilizing tag for challenging protein and #peptidesynthesis by #NativeChemicalLigation reviewed (Yoshiya at Peptide Institute, Osaka) https://t.co/l1tEE7E1LM
Wow, fantastic paper on a very promising new #peptide crypto thioester for #NativeChemicalLigation. Very interesting read. I want to try it out soooon. Excited 😆
Latent thioester formation from a cysteinylprolyl imide (CPI) peptide @ChemicalScience https://t.co/Uz4rWy6shv Utilizes the groups previously developed rapid Acm deprotection #propepchem
#NativeChemicalLigation at thio-lysine revisited - positioning of the thiol at the beta position is reported to yield selective ligation at the alpha amino group in @JOC_OL https://t.co/Mr4wfuh4ML
Excited to see our paper on isolation of staphylococcal AIPs now online @NatureChemistry. Great effort from co-authors and in particular first author @BengtGless. @HiIngmer @UCPH_health #AIPs #QS #NativeChemicalLigation Check it out at https://t.co/2pqhMXJUP2
Just accepted in @angew_chem from Juan B. Blanco-Canosa introducing further possibilities with #NativeChemicalLigation using an extended method based on the Dbz linker https://t.co/sPfhIphtc7
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