Top Tweets for #OrphanGPCRs
Innovative strides in healthcare, like @isip_tkg's GPR17 discovery, are pivotal.
As a tech exec, the prospects for orphan GPCRs & drug research thrill me.
Which other "undruggable" targets could we reveal?
#HealthTech #BioTech #Innovation #DrugDiscovery #OrphanGPCRs
https://t.co/ZA7QOdV3KV
プレスリリースを出しました
今回はオーファンGPCRで知られるGPR17を攻略するソリューションを開発して実証しました
#OrphanGPCRs are those for which no endogenous ligands or functions are known. Here is a study from @Kavita_Babu_ lab showing expression pattern of SRX-97 odorant receptor
https://t.co/4wBUtU2nGD
2. 🎯 TARGETS / MECHANISMS THAT MODULATE KEY CIRCUITRY
Identify novel or existing targets enriched in key circuitry and use advanced mechanisms in drug action to develop compounds that can selectively modulate this circuitry
#OrphanGPCRs #Allosterism #BiasedLigands
Don't forget to tune in to @3RRRFM 11AM tomorrow to learn about #20phds20mins on @einstein_agogo!! Let's see if I can squeeze all things #MouseTouchscreen #TranslationalResearch #OrphanGPCRs #CognitiveDeficits #Schizophrenia in a 2 minute interview with @DrShaneRRR! 🤞🤞
Just had a briefing session with this amazing group of PhD students ahead of Sunday's #20phds20mins broadcast on @einstein_agogo @3RRRFM. We are celebrating 30 years on air and the upcoming #Radiothon2020. Join us at 11am.
#GPR142 is one of my favourite #GPCRs. Not only because I contributed to this story characterising aromatic amonoacids as its agonists but simply because #orphanGPCRs are fascinating! Well done Molpharm lab @uni_copenhagen! @MolMetab
From Thue Schwartz et al: The aromatic amino acid sensor #GPR142 controls #metabolism through balanced regulation of #pancreatic and #gut hormones
https://t.co/0k3Ql5yVzT
#glucose #aminoacid #Gprotein
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