Top Tweets for #Pyropotosis
Global #GasderminD/GSDMD KO reduced #ThoracicAorticDissecition #IntramuralHematoma He in🐭+BAPN (0.2%) +locally applied Elastase
Interesting findings!
Which cell types in dissected🐭👤aortas undergo #Pyropotosis? #Inflammasome activity? Or GSDMD➡️other modes of death
Zhihua Jiang lab bioRxiv 2024
https://t.co/jjz6nDaAJz
Sox10, a central hub for Mφ-like transdifferentiation of #SmoothMuscleCell #VascularInflammation #Pyropotosis
PI3K-Akt->
phospho-Sox10->
TNFα-dependent Sox10 lactylation->
pro-inflam; pro-death
RGS5⏬PI3K-Sox10 axis
@CellReports 2023
https://t.co/g3J5VmzHDb
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