Top Tweets for #RandomizedTrials
Ruxolitinib Cream Shows Strong Benefits in Atopic Dermatitis
A new updated #metaanalysis of five #randomizedtrials (n=1912) confirms that #ruxolitinib cream significantly improves #atopicdermatitis outcomes compared with vehicle.
✨ Key findings:
• Higher rates of #IGA treatment success at 4 and 8 weeks
• Significant improvement in #EASI75 and #itch reduction
• Consistent benefits across ages and doses
• Safety profile comparable to vehicle, with no increased risk of #adverseevents
📌 Takeaway: Ruxolitinib cream is an effective and well‑tolerated #topical option for managing atopic dermatitis.
🔗 https://t.co/ZVb1YW0VQd
#pai_journal #systematicreview #ruxolitinibcream #AD @MartinCevallosC
🧪 Randomized clinical trials in cardiac surgery: necessary—but exceptionally difficult to perform.
📘 EJCTS ↓
🔗 https://t.co/Ll87V3K2z2
📝 SECCE ↓
🔗 https://t.co/FwC5YoPAVi
#CardiacSurgery #RandomizedTrials #ClinicalResearch #EJCTS #SECCE
#RandomizedTrials in individual patients – #Nof1 #RCTs – provide the highest certainty evidence of treatment impact in an individual. The epitome of best clinical practice. This article gives a step by step for setting up and running an N of 1 trial.
https://t.co/Eg0DomlDu7
🙈
#RandomizedTrials often claim to be #blinded yet are prone to inadequacies in their methods.
In this #JGIM #Perspective, #ClinicianScientists @Sunnybrook provide a cautionary framework for interpreting blinding in #EBM
https://t.co/R8WMQFKqQD
#CochraneDaily On Banana Day, there are more than 100 reports of trials of banana products in @CochraneLibrary CENTRAL #NationalBananaDay https://t.co/VWi3KJZfCg #RandomizedTrials
The elusive forest plot is demystified in the #BJJ Online Research Methods & Paper Review Course!
Book now for June or November!
#ResearchMethods #MetaAnalysis #RandomizedTrials #Orthopedics
https://t.co/LvYeOrf98R
Packed room for wine & cheese session with @_MiguelHernan at #IWHOD2023 in Athens.
For drug repurposing, decisions to graduate compounds to #randomizedtrials have been based on preclinical data.
How do we incorporate clinical (#observational) data to this process? Should we?
The European Organisation for Research and Treatment of Cancer (@EORTC) endorses #TargetTrial emulation with #RWD.
An organization with unmatched expertise in the design of #randomizedtrials embraces their explicit emulation when using observational data.
https://t.co/JjZnvdwzqQ
The deadline for submissions to the upcoming Special Issue on Integration of Observational Studies with Randomized Trials is extended until JUNE 15, 2022.
For more information, please visit our website:
https://t.co/LCpdvFkKsV
#causalinference #randomizedtrials
NEW: A #TargetTrial emulation to study the comparative effectiveness & safety of fertility treatments, led by @Jennifer_Yland.
Another example of how #observational databases can be used to extend the results from (necessarily small) #randomizedtrials for better decision making.
New findings on #pregnancy and #neonatal outcomes following treatment with clomid versus letrozole for ovulation induction:
A 🧵on our new study in Human Reproduction
1/5
https://t.co/PzeltHWgMG
An early #guideline on #COVID before the #randomizedtrials came in shows how a rapidly produced guideline when evidence is limited can provide direction – and primarily ensure caution against indiscriminate use of unproven therapies.
https://t.co/DqTYMSWGDW
We invite you to submit papers for the upcoming Special Issue on Integration of Observational Studies with Randomized Trials in the JOURNAL OF CAUSAL INFERENCE.
Deadline: Dec 15, 2021
See the full call for papers at:
https://t.co/kyhcXdSnH8
#causalinference #randomizedtrials
@Angelasfreenews Hope you can sleep well at night, because these News about Mass #NeoFascist⚠️ #Experiments💉+ #RandomizedTrials🏥 on both Healthy People and those Affected by #Immunodeficiency🚨 Give me Headaches & Nightmares about our not so distant #DystopianFuture⚠️
STOP #VaccinePassports 🛑
@DrCathyCraven is presenting to our Division about The trials and tribulations of #spinalcordinjury clinical trials
#clinialtrials #rehabilitation #physiatry #randomizedtrials
#PatientsasPartners #patientsincluded
How to design #largescale #randomizedtrials on #studentachievement?
📢Excited to announce our newly published paper compiling #multilevel design parameters w/ Oliver Lüdtke, @ArteltCordula, & Martin Brunner in #JREE
https://t.co/NbmRjdXHkA
#educationaleffectiveness #poweranalysis
Yet another beautiful theory slayed by ugly facts. And therein lies the essence of scientific enquiry. Reiterates why we need robust #randomizedtrials to guide management decisions. #COVID_19 @credoworkshop @ACORDISM @spkalantri @AnantBhan @epigiri @GKangInd
The RECOVERY Data Monitoring Committee reviewed data on patients randomised to convalescent plasma vs. usual care. The preliminary analysis based on 10,406 randomised patients with 1873 reported deaths shows no significant difference in the primary endpoint of 28-day mortality.
5/
Also, so much talk about extending results from #randomizedtrials to a target population.
But so little guidance on how to design data collection.
Here we provide a unified description of study designs for #transportability and #generalizability.
https://t.co/913EfyDRNu
#SooninAJPH "Should e-cigarette regulation be based on randomized trials or observational studies?" @PublicHealth @AMJPublicHealth
#ecigarette #ecigs #research #randomizedtrials #observationalstudies
Missed a talk? Recordings from the conference on #philosophy of biomedical research are now available.
Talks by scientists, medical doctors and philosophers.
https://t.co/zNyG0kdspq
#cancer #microbiome #immunology #BigData #epidemiology #randomizedtrials #stemcells #EBM
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