Top Tweets for #ReviewCourse
#ReviewCourse #ACR25 MAS treatment:
🔹Corticosteroids remain first-line
🔹 Anakinra (anti-IL1) improve survival in severe MAS
🔹 Emapalumab (anti-IFNγ) 93% remission in refractory cases; FDA-approved for steroid-refractory Still’s-MAS
#ReviewCourse #ACR25 MAS:
🔹Hyperactivation of T cells and macrophages leading to a cytokine storm with cytopenias, liver dysfunction, coagulopathy, and extreme hyperferritinemia
🔹 Most frequent in Still’s disease
🔹 Part of the secondary HLH spectrum
#ReviewCourse #ACR25 Eosinophilic fasciitis
👀 Key clue➡️look at the distal digits
💊1️⃣Systemic corticosteroids (first-line)
🔸Immunosuppressants:MMF >MTX
🔸IVIg for refractory cases
🔸3rd line: mepolizumab, tocilizumab, rituximab or JAKi
⚠️ Delayed diagnosis> 6m worsens outcomes
#ReviewCourse #ACR25
🔹Autoimmune encephalitis, primary CNS angiitis, and autoinflammatory “cytokine storm” syndromes.
🔬 Diagnosis guided by MRI and autoantibody profile.
💊 Therapy: Rituximab, cyclophosphamide, and IL-1/IL-6/TNF blockade depending on phenotype.
#ReviewCourse #ACR25 vasculitides & CNS involvement
🔹 Takayasu,PAN & ANCA-associated: CNS dysfunction rare but life-threatening.
🔹 GCA/PMR:overlapping inflammatory spectrum.
🔹 Behçet’s: parenchymal vs. cerebral venous thrombosis forms.
💊 Therapy: cyclophosphamide or TNF/IL-6
#ReviewCourse #ACR25 vasculitides & CNS involvement
🔹 Takayasu,PAN & ANCA-associated: CNS dysfunction rare but life-threatening.
🔹 GCA/PMR:overlapping inflammatory spectrum.
🔹 Behçet’s: parenchymal vs. cerebral venous thrombosis forms.
💊 Therapy: cyclophosphamide or TNF/IL-6
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#ASAM #ReviewCourse #AddictionMedicine
Calcium metabolism in sarcoidosis.
Granuloma/macrophages production of 1,25 cholecalciferol.
Only 10 to 20% have hypercalcemia .
#ACR25
#Reviewcourse
Dactylitis management in PsA:
Acute: pain and swelling
Chronic: painless swelling
Broad ddx
No role for LEF or SSZ
#ReviewCourse #ACR24 @RheumNow
Multimorbidity reduces response to b/tsDMARDs in RA. We can make a difference by treating the whole person!
Amazing talk by Dr Iain McInned to wrap up #ACR24 #ReviewCourse.
@RheumNow
Hypophosphatasia, consider it as a cause of osteoporosis and other rheumatic conditions such as chondrocalcinosis #ReviewCourse #ACR24
#Calcinosis is tough to treat!
Here’s a nice summary of options to consider in #Scleroderma & #DM including biologics (RTX in SSc and Tofacitinib in DM) and Minocycline
👉 Needs individualizing!
Excellent talk by Dr. Valenzuela
#ACR24 #ACRambassador
#ReviewCourse
@ACRheum
“Small fiber neuropathy is an extremely common finding in hundreds of medical conditions-most of which are not involving pain” -Dr Daniel Claw
Should we stop pursuing biopsies?
Should we redefine this disease?
#ReviewCourse #ACR24
Very cool. FM scoring system( surrogate measure of degree of nociplastic pain) that predicts treatment response with individuals receiving peripherally- directed therapies.
#ACR24
#reviewcourse
It’s not just pain; it’s a complex set of mechanisms that we must continue to understand and learn better #ReviewCourse #ACR24
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