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I need to tell you something that makes me angrier than anything else in medicine. 60 randomized controlled trials. 323,950 patients. Every cholesterol-lowering drug ever made. Statins. PCSK9 inhibitors. Ezetimibe. One question. Did lowering LDL cholesterol make people live longer? Look at the chart. Every dot is a trial. The red line is zero benefit. If these drugs saved lives, the dots would be above the line. They are not. They reduced LDL by up to 80%. Nobody was saved. But that is not what makes me angry. What makes me angry is that millions of people believe they are safe because their LDL is low. Their doctor says "your numbers look great." They go home and never think about it again. Meanwhile the 12 things that actually cause heart disease are silently building inside them. Nobody is checking. Nobody is testing. Because a cholesterol number gave everyone a false sense of security. That is not a failure of medicine. That is a fraud. Ennezat et al. Journal of Cardiovascular Pharmacology. 2023.