Top Tweets for #ScaffoldHopping
✨New Spark™ databases!
Newly updated databases from ChEMBL and SureChEMBL are now available for #ScaffoldHopping within Spark.
https://t.co/8xNi1KQvil
#pharma #biotech #medchem #compchem #computationalchemistry #CADD #digitalchemistry
Very proud to share our deep dive Perspective on #scaffoldhopping in CNS #drugdiscovery. Massive congrats to lead authors Tim and @TazGaz98 from @KassiouGroup for their immense hard work throughout multiple lockdowns to get this over the line. https://t.co/pOw39Ll9gO
And we developed a graph-based algorithm automatically finding distance restraints for linked dual topology #FreeEnergyCalculations, that can also deal with #scaffoldhopping Transformations and #multistate Systems!
See how Spark™ can generate highly innovative ideas for your project to explore chemical space and escape IP and toxicity traps, and request an evaluation
https://t.co/yH0i6eMFN4
#DrugDiscovery #ScaffoldHopping #MoleculeDesign
Learn how to carry out a scaffold hopping experiment in Spark™, the leading solution for scaffold hopping and R-group replacement
https://t.co/EjxfICKaGH
#DrugDiscovery #ScaffoldHopping #MoleculeDesign
Rapid approach to new scaffold generation
November 12th, 11am - 1pm
Register free https://t.co/pG0Acfvq9u
#ProtectIP #IntellectualProperty #ScaffoldHopping #NovelIdeas #Bioisosteres #MedChem #CompChem #SoftwareWorkshop
See how to update databases for Spark, your #scaffoldhopping and R-group exploration solution, some of which are released on a monthly basis.
https://t.co/fgxJrit6Ch
#CompChem #DrugDiscovery #MedChem
F. Grisoni, G. Schneider, et al. @ETH_DCHAB made a #machinelearning workflow to identify several compounds with multitarget profiles on #Alzheimers-disease-related targets #compchem #virtualscreening #scaffoldhopping https://t.co/UwtGe7FWJJ
Review of Novartis paper demonstrating how a traditional #scaffoldhopping experiment, using Spark, led to the identification of novel oxazolidinone and isoxazoline LpxC inhibitors active on Gram negative bacteria
https://t.co/LMLXA7w95T
#CompChem #DrugDisccovery
S. De Jonghe et al. @LeuvenU report a #scaffoldhopping strategy to identify cyclin G associated #kinase inhibitors #heterocycles #drugdiscovery https://t.co/wLM5E3Kzj6
B. Wuensch et al. @WWU_Muenster @ETH replaced the 4-benzylpiperidine scaffold of potent GluN2B antagonists with fluorinated structural elements #drugdiscovery #NMDAreceptor #scaffoldhopping https://t.co/frjVk1n9k8
January 2018 newsletter
Release of Spark V10.5 for scaffold hopping and bioisostere replacement, video tips and tricks for Spark, Flare and #ActivityMiner, citations, editorial and registration open for The Cresset User Group Meeting.
#CompChem #cugm18 #ScaffoldHopping
Spark V10.5 release offers improved usability and flexibility, and new science
https://t.co/rTQIQAkDIE
#ScaffoldHopping #BioisostereReplacement #CompChem
Chemical Reaction as published in @IPTmag https://t.co/HH3fTGh4U6 #ScaffoldHopping #CompChem #SyntheticChemistry #CaseStudies
Second HIV-1 entry inhibitor submitted by my collaborator @ Drexel. More writing to do, then a new pet project. #science #scaffoldhopping
Last Seen Hashtags on Sotwe
Trends for you
Most Popular Users
Elon Musk 
@elonmusk
241.6M followers
Barack Obama
@barackobama
119M followers
Cristiano Ronaldo
@cristiano
114.2M followers
Donald J. Trump
@realdonaldtrump
111.8M followers
Narendra Modi
@narendramodi
107.2M followers
Rihanna
@rihanna
98.7M followers
NASA
@nasa
92.4M followers
Justin Bieber
@justinbieber
91.8M followers
KATY PERRY
@katyperry
89.9M followers
Taylor Swift
@taylorswift13
83.8M followers
Lady Gaga
@ladygaga
75.3M followers
Virat Kohli
@imvkohli
73.2M followers
Kim Kardashian
@kimkardashian
70.8M followers
YouTube
@youtube
68.8M followers
Neymar Jr
@neymarjr
66.2M followers
Bill Gates
@billgates
65M followers
Selena Gomez
@selenagomez
63M followers
The Ellen Show
@theellenshow
62.3M followers
CNN
@cnn
61.8M followers
X
@x
60.7M followers