#SundayJournalClub - Twitter Hashtag

about 4 years ago · Copenhagen

#SundayJournalClub is back after a hiatus. Today we highlight two important structure papers. First is the structure/function analysis of SC4, #AMPK activator with tendency for α2-selectivity that is also capable of potently activating β2 complexes. 1/5 https://t.co/sH3539QYqU

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W09 Today we feature a recent study in @NatMetabolism by the Ryden and Mejhert groups @karolinskainst where they show how energy #metabolism imbalance in human #adipose, can lead to the development of inflammation & insulin resistance https://t.co/wLEIuOfwQw

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W08 Today we feature the latest publication from @MetSigLab & Peterson labs in @CellReports where they discover an #AMPK α2 S345 specific phosphorylation switch that controls its lysosomal targeting and activation 1/3 https://t.co/qSni27LFAT

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W06 For this week's journal club, we highlight an extensive review article published in @AnnualReviews focuses on the role of #exercise induced activation of #AMPK in the regulation of system #metabolism. 1/2 https://t.co/BdXseuG1S7

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W04 This week we are featuring an interesting paper in @NatMetabolism that highlights the role of #BCAA #metabolism in #adipose #browning & thermogenesis 1/4 https://t.co/qsbO0loh3C

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W03 This week's highlight is the recent paper from the Rabinowitz lab where they elegantly demonstrate that for major circulating metabolites, there is a linear relationship between breakdown in the TCA cycle & their systemic levels 1/3 https://t.co/Mah0WmW36f

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Sakamoto Lab @LabSakamoto

over 4 years ago

#SundayJournalClub #W02 This week we are focusing on #Glycogen #metabolism and featuring two recent fabulous papers that reported it's "non canonical"/ lesser known roles in a) #browning of #adipocytes and b) #macrophage mediated #inflammatory processes 1/3

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Sakamoto Lab @LabSakamoto

over 4 years ago

We are introducing a #SundayJournalClub, where we will be highlighting 1 exciting paper (new or old) every Sunday. First up, we have this great review of the complex cellular and physiological mechanisms linking obesity with diabetes by Phil Scherer et al in @Cell_Metabolism

Cell Metabolism @Cell_Metabolism

over 4 years ago

Why does obesity cause diabetes? https://t.co/ELt2KjNnNA

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