Top Tweets for #TGSThursday
The 2023 Takara Bio USA year-in-review Wrapped is here. Everything you do helps make your customers better and supports their good science!
#ThatsGoodScience #TGSThursday #Wrapped
Can immune checkpoint molecules be therapeutic targets in cats, as they are in humans and dogs?
New findings from @tohoku_univ_med published in @SciReports suggest they can: https://t.co/j81FW58WYN
#NationalCatDay #TGSThursday
Is your #polymerase up to the task?
For #NextGenerationSequencing (#NGS), not all #enzymes perform the same. Learn how you can make sure your #PCR polymerase is a top performer: https://t.co/FStlpMCMYd
#TGSThursday #DNA #RNA
How can we achieve atlas-scale single-cell #ATACseq at low cost? Scientists @OHSUKnight use combinatorial indexing with nanowell chips to increase cell throughput by 52x! Sequencing mapped mouse-brain cell types.
Read @genomeresearch: https://t.co/VSXhFjynp0
#TGSThursday
Killer EVs (#ExtracellularVesicles) could be a future weapon in #oncology. Study: https://t.co/n3IBUV91BK
Researchers at @univ_paris_cite @Inserm delivered a coup de grâce to target cells with EVs bearing diphtheria toxin, engineered with In-Fusion® cloning. #TGSThursday
Why do targeted drugs so often fail #ColorectalCancer patients with #BRAFV600E mutation? Study: https://t.co/z7o0YEuDep
Researchers at @vallhebron ran #WholeExomeSeq using ThruPLEX® kits, identifying other #biomarkers associated with better survival rates. #DNAseq #TGSThursday
#TGSThursday
Sometimes, a healthy gene + abnormal #RNAprocessing = disease. It's hard to predict from DNA! But scientists at @UW & @Stanford just made it easier. Their new #NeuralNetwork model better matches 3’-end mutations to clinical disease.
Study: https://t.co/xfmmI22btN
#TGSThursday
What could #Bcells, #microglia, and #neutrophils be doing at a #SpinalCordInjury site?
Study: https://t.co/a59SoebH5Z
Scientists from @NeuralStemCells ran #scRNAseq using the ICELL8® cx Single-Cell System to begin mapping out these immune cell interactions. #SCI
Need #RNA from a #cancer #biopsy?
Running #RNAseq on formalin-fixed paraffin-embedded (FFPE) samples or fine-needle aspirations is tricky! @univ_paris_cite scientists found our kit, SMARTer® Stranded Total RNA-Seq Kit v3 – Pico, did it best!
https://t.co/202BeY6vS5
#TGSThursday
#TGSThursday
Scientists at @fredhutch cleverly circumvented an #epigenomics workflow challenge. By mixing antibodies in their CUT&Tag protocol, they profiled active + repressed chromatin regions simultaneously.
The method, featuring our ICELL8 cx system: https://t.co/VqFmbjTMgE
#TGSThursday Cancer #immunotherapy clinical trials often fail. #TCRseq and #BCRseq can salvage valuable lessons. A Phase 2 study didn't boost T cell activity against #TNBC; BCR profiles were tied to a stronger response to therapy #bcsm Read the full study: https://t.co/PyguPRZ7io
#TGSThursday
Quick! What kind of bacteria are swirling along the Jiulongjiang River?
Scientists in Xiamen, China, used SmartChip #PCR + @PacBio #sequencing to create a novel method of profiling #microbial diversity & interactions in water samples.
Study: https://t.co/7CH6gUP3FT
#TGSThursday
A path forward in fertility?
An @art_fertility team led by @NeelkeDeMunck compared embryo development after conventional #IVF and #IntracytoplasmicSpermInjection. The study combined #TimeLapseMonitoring and #NGS #PGT for aneuploidy.
Study: https://t.co/aRBnEBY0yq
#TGSThursday How can we end the HIV epidemic? At the @UNC HIV Cure Center, a team describes the ex vivo function of combined latency reversal agents. This is an important step in an #HIVcure strategy. View the publication: https://t.co/XTE3kSBnrM @jclinicalinvest @TAGHIVscience
#TGSThursday
Researchers at @UTHealthHouston demonstrate effectiveness of a bispecific antibody approach to penetrate the #bloodbrainbarrier (#BBB) in a mouse model of #glioblastoma
Read: https://t.co/zaNAzRoMWW
@CPRITTexas
#TGSThursday
Researchers from Schneider Children's Medical Center of Israel found that constitutive activation of IL7RA has the potential to initiate preleukemia.
Read more: https://t.co/REMUYHGIcb
#Bcell #ALL #Leukemia #Pediatric #Cancer
#TGSThursday
Looks like these scientists have got all their ducks in a row.
🦆🦆🦆
Learn how their research may serve as a rich resource for understanding the genetic basis of avian #evolution and #BirdFlu.
#H5N1 #AvianInfluenza #Virology
Read more: https://t.co/FbClxzEo0Z
#TGSThursday
Researchers from @fredhutch mapped fusion-specific targets across the genome for diverse KMT2A oncofusion proteins, often associated with acute myeloid and lymphoid leukemias.
Read more: https://t.co/idOgDGT1w1
#AML #ALL #leukemia #oncology #cancer #research
#TGSThursday
Jared Spidel from @EisaiUS (formerly @Morphotek) used the In-Fusion seamless cloning kit to help develop a robust high-throughput mAb discovery and production system.
Read more: https://t.co/ZeoNuYMwmx
#monoclonal #antibodies #cloning #gene #drugdiscovery
#TGSThursday
Researchers @fredhutch developed “MulTI-Tag”, a method to analyse multiple histone marks and distinct chromatin-associated proteins within individual cells.
Congrats @mpmeers and team!
Read here: https://t.co/MiD8pHrGSW
#ICELL8 #gene #epigenetics #cell #disease
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