Top Tweets for #TH22
$SNY peak sales of €5B+ for #amlitelimab anti-OX40L for #atopicdermatitis + #asthma.
$CRVS MC $550M, #ITKi #soquelitinib more potential?:
- oral
- further upstream before #Tcells differentiate, blocks #Th2 #Th9 #Th17 #Th22
- stops #ILC2 cells
- blocks 10+ cytokines
- ⬆️ #Tregs
Based on location of pathways and cell types affected, I would expect $CRVS #soquelitinib (SQL) to perform even better than $SNY #amlitelimab #OX40L inhibitor.
SQL is oral, more upstream than amlitelimab so stops naive Tcells from differentiation and stops more cell types #ILC2 #Th2 #Th17 #Th22 + downstream cytokines, ⬆️ #Tregs + ⬆️anti-tumor memory CD8+
Amlitelimab is injection, reduces activation of already differentiated Tcells and downstream cytokines, should increase Tregs, but blocking OX40 may actually impair CD8+ cancer fighting cells/memory-type.
$SNY mAb #Amlitelimab blocks #Tcell #OX40 in #atopicdermatitis and blocks #Th2 #Th17 #Th22 + downstream cytokines. Long-lasting effect 28 weeks after treatment!
Bodes well for $CRVS #ITK inhibitor #soquelitinib:
-oral, safe
-⬆️ #Tregs
-blocks 10+ cytokines
-long-lasting/memory?
New data for amlitelimab published in JACI https://t.co/nJCBERCEHt
"nadie está con vos" si supiera que acá afuera todos estamos subidos a la frodoneta y que cuando apenas toque placa se va a ir a la mierda, se cae de orto
#GH22
https://t.co/LmHh0OmTM2
Jedino što je sa njima sigurno jeste da će naša država biti NESIGURNO!
Mi volimo ovu državu, ali ne volimo lopove! 🇧🇦✅
Glasajte za promjenu! ❤️
#TarikHalilović #TH22 #Tarik #Halilović #dostapriče #idemoraditi #Izbori22 #OpćiIzbori22 #ZDK #Visoko #Zenica #Tešanj #Kakanj
Pridružite se našoj Viber zajednici i pratite sva aktuelna dešavanja u ZDK. 📞💬
Dobrodošli! ✊🏻♻️
Link: https://t.co/wqeANMpVrv
#TarikHalilovic #TH22 #IdemoRaditi #Visoko #ZDK #BosnaiHercegovina
U državi u kojoj radnik mora da zaradi 1400 KM da bi dobio prosječnu neto platu u iznosu od 900 KM, dijeli se sadaka od 100 KM najugroženijim grupama stanovništva, i to se naziva stabilnom ekonomijom.
Dosta je, Fadile!
#idemoraditi #fadil #th22
Više na: https://t.co/JZ8d0sHPj1
#JI_TopRead from @virusmonologues @Burgers_Lab @UCT_news | Characterization of #Mycobacteriumtuberculosis-specific #Th22 cells and the effect of #tuberculosis and #HIV #coinfection #ReadTheJI #immunology #AuthorChoice #TB #Tuberculosis https://t.co/OmaYs3B1yj
Bakir Izetbegović bi trebao da zna da porodici u Bosni i Hercegovini nijedan robot ne može zamijeniti dijete, sina, kćerku, rođaka ili bilo kojeg člana porodice bilo kakav robot.
Više: https://t.co/KADVkhmS6t
#TH22 #BiH #Visoko #ZDK #OpciIzbori22 #Izbori22 #BakirIzetbegovic
Ove godine ću biti kandidat za Skupštinu Zeničko-dobojskog kantona na listi Koalicije Država! - Mirsad Hadžikadić (Platforma za progres). 🇧🇦
Idemo raditi! ✊🏻♻️
#TarikHalilovic #TH22 #IdemoRaditi #OpciIzbori2022 #ZDK #BosnaiHercegovina
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