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Then you've got to check out my 5 Day Holiday Sales #TSPChallenge, sign up here ➡️ https://t.co/GzakFQoERg

I’m excited to be joining a Free Training: What's Working Now: How to Drive Consistent Traffic and Leads into Your Sales Pipeline #TSPChallenge: https://t.co/Z3CGlB7TjK via @lamartyler
Solo 24h para el #TSPCHALLENGE2
¿Podrá nuestra caja TSP 📦 sobrevivir a los golpes de un boxeador profesional? 🥊🥊🥊
📍Mañana jueves 24 de enero a las 18:00 lo descubrirás..
#TSPChallenge
Mira el avance de #TSPChallenge2 👇
📍 Próximo jueves 23 de enero
⏰ 18:00
☝️Solo en las redes social de TotalSafePack
Si quieres puedes ver el anterior capítulo, #TSPChallenge 1 haciendo clic aquí: https://t.co/Ie2nDmljTs
Nuestro CEO @DavidGorgues muestra el video del #TSPChallenge en #bizexporta #Bizbarcelona #BizBarcelona19 @cambrabcn

Thank you to Dr Vanya Jaitly for providing the past two weeks’ #TSPchallenge cases! Dr Jaitly is a third year Pathology Resident at UT Health Science Center in Houston. She is interested in #hemepath and #MolecularPath @JaitlyVanya

ETV6-NTRK3 gene rearrangement + by FISH. Dx: Secretory Carcinoma - defined by t(12;15)(p13;q25). Ddx on morphology
includes acinic cell carcinoma. Characteristically S100 +, Mammoglobin + and DOG1 -.
Case courtesy Dr. Jeffrey Conyers. #HeadNeckpath #TSPchallenge @JaitlyVanya

What are your differentials of this tongue lesion in a young female? #HeadNeckpath
#TSPchallenge @JaitlyVanya

IHC in photos. FISH was + for EWSR1 rearrangement. Dx: Clear Cell Sarcoma. CSS is a translocation associated
sarcoma with melanocytic differentiation. LN mets often. Case courtesy Dr Lin Zhang. @lzhang003497248 #BSTpath #TSPchallenge @JaitlyVanya

What are your differentials for this foot mass? MRI showed an encapsulated mass not associated with malignant tendencies. High power pictures and IHC to follow. #BSTpath
#TSPchallenge @JaitlyVanya @lzhang003497248

CD138 + monoclonal PC’s. EM: rhomboid crystals. Dx: Crystal storing histiocytosis, multiple myeloma. Crystalline material in non-neoplastic proliferating histiocytes. Assoc. w/ lymphoproliferative neoplasms. Look for the hidden PC’s! #Hemepath
#TSPchallenge @JaitlyVanya

What are your differentials of this biopsy from pathologic fracture sites in tibia and fibula? What immunostains should be performed? #Hemepath #TSPchallenge @JaitlyVanya

Also - for S100, Desmin, p63, CD31 and ERG. Vimentin +
Diagnosis: Epithelioid Sarcoma.
Epithelioid sarcoma: First described in 1972, Proximal Type more aggressive. May metastasize to lymph nodes. Loss of INI1 expression is characteristic. #BSTpath #TSPchallenge @JaitlyVanya

High mag: medium-large cells, some pleomorphism, abundant eosinophilic cytoplasm, indistinct cell borders. Few spindled and more epithelioid cells (A), Ossification (B), Extravasated RBCs, tumor impinging on nerve (C). What IHC would you do? #BSTpath #TSPchallenge @JaitlyVanya

What are your differentials for this slowly growing mass involving the superficial and deep soft tissues of the wrist? High power pictures to follow. #BSTpath #TSPchallenge @JaitlyVanya

Day 4: IHC was + for HHV8, MUM1, focal + CD138, EMA, CD45, and CD3. - for CD20 and PAX5.
Diagnosis: Primary Effusion Lymphoma:
Rare AIDS related lymphoma of B-cells derivation. Always with HHV-8 infection and usually with concomitant EBV infection.
#TSPchallenge @ErinGarrettMD

Day 3: Patient was discharged on HAART following a dx of Kaposi Sarcoma. 1 week later he returned with SOB. Cytology shows a lymphomatous effusion with immunoblastic to plasmablastic morphology. What IHC would you do to arrive at a final diagnosis? #TSPchallenge @ErinGarrettMD

Day 2: Following admission, the patient was noted to have hyper-pigmented lesions on his proximal arms and thighs. His hemoptysis was secondary to large friable mass found on endoscopy. #TSPchallenge @ErinGarrettMD

Our case challenge this week! Follow the case each day and post your guesses or comments #TSPchallenge @ErinGarrettMD

Case Challenge Week #1
And...The diagnosis is Diffuse Pulmonary Meningotheliomatosis. CT scan showed numerous bilateral small nodules. A rare case with few reports in the literature. #TSPchallenge https://t.co/vQxCE6rqf7

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