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Latest episodes of #ThisMedLife #podcast
Thank you to all of our guests, listeners & production crew (@TimWhiffen, Tom Bussenschutt & @stevedavis)
Available on all podcasting services & Spotify
And also don’t forget series 1 #ThisPathLife
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#MedTwitter
Histology flash card
Malignant mesothelioma
Rare
Strong assoc asbestos exposure
Oft 5-7th decade
Dx average 2-4 decades after asbestos exposure
Median survival ~1yr
Histo variants
-epithelioid
-sarcomatoid
-mixed
Ep 8 #ThisPathLife #podcast in the backlog of @ThisMedicalLife
Histology flash card
Medullary thyroid carcinoma (MTC)
1-2% thyroid cancers
70% sporadic (40-60yrs)
30% familial (av 35ys)
Neuroendocrine tumour (C cells)
⬆️serum calcitonin & CEA
Familial have germline RET mut
Discuss MEN syndrome #ThisPathLife #podcast Ep 40
#PathTwitter
35 episodes (80 if you include #ThisPathLife #podcast)
Our guests include authors, doctors, specialists, and researchers
Get up to date in the most entertaining way possible
#MedTwitter
#PathTwitter
Histology flash card
Endometriosis
~10% reproductive age♀
Risk factors:
-FHx
-Early menarche
-Late menopause
-Nulliparity
-Heavy menstrual bleeding
Locations
Ovary/ovarian fossa 67% & 32%
Uterosacral ligaments 46%
Pouch of Douglas 30%
Bladder 21%
Ep 19 #ThisPathLife #podcast
2 years of #podcasting
83 episodes
2 series
Interviewees: Drs, Professors, Pathologists, Specialists, Authors, CEOs, and a Nobel Laureate
#ThisMedLife #podcast
#ThisPathLife #podcast
Available on all podcasting services & Spotify
Episode listing 👇
Histology flash card
Medullary thyroid carcinoma
Av 4th-6th decade
75% sporadic
Oft solitary thyroid nodule
At presentation
70% Pts Mets (+ve nodes)
15% dysphagia, hoarseness
Serum calcitonin may correlate➡️ mass
Familial➡️MEN syndrome discussed
Ep 40 #ThisPathLife #podcast
Histology flash card
Mesothelioma
Rare
Majority >60yrs
Hx of asbestos exposure
Accelerated by 🚬
Presentation
Gradual onset chest pain, dyspnoea, hoarseness, night sweats, dysphagia
Imaging: pleural thickening
Dx biopsy
Ep8 #ThisPathLife #podcast
#MedTwitter
#PathTwitter
World War 2
German advance into France in May 1940 took 3 days to reach Sedan where the French expected it to take 2 weeks
The secret weapon: a drug produced by German pharmaceutical Temmlerwerke
The drug ‘Pervitin’
We know it as Methamphetamine
Ep 22 #ThisPathLife #podcast
Histology flash card
Endometriosis
~10% ♀
Fertility issues, dysmenorrhea, heavy periods, dyspareunia
Locations
-Ovary (67%)
-Ant/Post cul-de-sac
-Post broad lig
-Pouch of Douglas
-Bladder
Histo
Endometrial glands & stroma outside uterine cavity
Ep19 #ThisPathLife #podcast
Histology flash card
Coeliac disease
~1/200
Bloating, malabsorption
Serology: tTG, EMA
Note: also test IgA (pts can have an IgA deficiency giving false -ve on serology)
Gold standard: biopsy
Histo
Mucosal inflam
Villous atrophy
Crypt hyperplasia
Ep 39 #ThisPathLife #podcast
Alexander the Great organised a drinking contest in honour of the death of philosophy tutor & mentor ➡️ Calanus
41 soldiers & Persian locals took part
He who drinks the most➡️wins🥇
The prize➡️talent of gold (26kg/57lb)
⬇️
All contestants died
Ep 12 & 17 #ThisPathLife #podcast
Histology flash card
Endometriosis
Ectopic endometrial tissue
~10% reprod age ♀
⬆️ with FHx, nulliparity, early menarchy (<11-13yr), late menopause
⬇️ with multiple births, extended lactation, late menarchy (>14yr)
Assoc with fertility issues
Ep 19 #ThisPathLife #podcast
1938: The Drunkometer
The first practical roadside breath testing machine
The size of a suitcase 🧳
Drivers blew into a balloon 🎈
Air was pumped into an acidified K+ permanganate ➡️ colour change = alcohol present
#MedTwitter #histmed
#ThisPathLife #podcast Episode 17
#ThisPathLife #podcast Ep 17
First ever drunk driver conviction
1897
George Smith
London cab driver
Had 2-3 beers
Crashed & broke a water pipe
Speed 8mph (~12kph)
Defendant argued it was 6mph b/c it was on an incline
Charge: being drunk, 20 schillings
New series #ThisMedLife
Antonine plague 165 CE
Roman epidemic lasted 15 yrs
Symptoms
-Fever
-Vomiting & diarrhoea (black ?blood)
-Swollen throat
-Cough
Skin eruption red/black papules that ulcerated
➡️symptoms 2 wks ➡️ most died
Up to 2000 deaths per day
Disease ?smallpox
#ThisPathLife #podcast Ep4
Coeliac flash card
Most common cause of intestinal malabsorption
1/200 people
Intolerance to gliadin (gluten)
Serology/antibodies
-TTG: tissue transglutaminase abs
-DGP: anti-deamidated gliadin abs
Gold standard
Duodenal bx: severe villous atrophy
Ep 39 #ThisPathLife #podcast
Cystic fibrosis flash card
Autosomal recessive
Caucasian carrier ~1/20
Live births 1/2500
CFTR gene
Impaired ENaC (epith sodium channel)
⬆️Na in sweat
⬆️viscous mucus
Case 18 yr♂ileostomy reversal
Histo: inspissated mucus in GI tract
Ep 44 #ThisPathLife #podcast
#PathTwitter
Released today
#ThisMedicalLife #podcast
An independent production & sequel to #ThisPathLife
6 episodes now available
Ep 1 Anaesthetic & surgery
Ep 2 Syphilis
Ep 3 SLE with @DamanLangguth
Ep 4 Urine
Ep 5 Egyptian mummies
Ep 6 MS with Dr J Leyden
1st Ep
https://t.co/oxCxufp872
Endometriosis (Ep 19)
#ThisPathLife #podcast
The tragedy of the wandering womb
Dysmenorrhea
Hippocrates
‘When they have borne children…she will be released from disease’
Middle Ages
Believed ‘suffocation of the womb’
17th century
Demonic/witchcraft
https://t.co/TfdSQHa85M
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