Top Tweets for #Thoraxicpath
#PulmPath #Thoraxicpath
#IHCpath
If you wondered about those crazy SLCC negative for NE markers and TTF1.
Here is one explanation
Fantastic post by @CaDxPath
You can subdivide lung small cell carcinoma into subtypes based on transcriptional regulators
Therapeutic significance still being investigated-but useful to know from diagnostic pathology point of view
Let me tell you about 'tuft cells' and why they're good to know about

Thymoma. There has been so much angst about this classification over the years but very little or nothing about these subtypes changes management.
BUT it does highlight the entire morphologic spectrum. I see AB the most. What subtype do you see most?
#thymoma #pathology

#Pulmpath #Thoraxicpath #CUP #Pathcasetosolve
Is amazing the engagement of #Pathologists on puzzling cases, pure passion for #Pathology ↘️↘️
1/2
Sharing this case from a colleague who is not active here:
An elderly male with cough.
CT showed multiloculated pleural fluid, VAT showed multiple nodular pleural masses.
IHC done at another center:
Calretinin, CK7/20, TTF-1 All negative.
Any thoughts?
#Pulmpath #Pathology

@ariella8 @mkbaine @thoracicpath @Juanfertwt @kis_lorand @MAHoureih @yro854 @smlungpathguy @lara_pijuan @AmparoBenito Hi Celina, thanks for the tag with this tricky case. Sorry so late but would favor poorly-diff carcinoma based on morphology and CK7+. For 11 cm probably hard to know if truly posterior mediastinum vs lung vs thymus. So hope other IHC marker in this differential were helpful!
#Pulmpath #Thoraxicpath #IHCPath So far the cells are positive just for CK7
Negative initial stains: CK 20,TTF1,P40,Calretinin, WT1,SOX10 ,SALL4 and Desmin
How would you proceed?
@angelpanizo1 @yro854 @kis_lorand @smlungpathguy @mkbaine @lara_pijuan @Dramanyhassany1 @MAHoureih
#Thoraxicpath #CUP #IHCPath #Mytrucutbiopsies Male on 50s .11 cm posterior mediastinal mass .Your favored DX and IHC request 😊🙏

#pulmpath #Thoraxicpath #IHCPath As promised here is the IHC on the case ,those intercellular bridges didn't lied 😊 Synapto negative.Thank you for engagement 🙏🙏@hopkinscyto @kis_lorand @smlungpathguy @nusrat_xahra @D4L14H @SSPgozaPath @djoud

Dr.Julian Sanz @JulianS61059757 nos anima a identificar correctamente los subtipos de adenocarcinomas pulmonares e intentar diferenciar los de mayor agresividad dentro del mismo subtipo 🤓 #CursoActualización2019

🔬 Hi @pathology friends! Ready for the next #natpathpuzzler 🧩? Well… here it is. Biopsy of a lung nodule in a patient with renal mass. Here is TTF1. Thoughts? Would you get any other stains?

Dear tweeples, do you think this lung tumor is a Combined Small Cell Carcinoma 🤨? Previous breast neoplasm (ductal carcinoma 8y ago). Female middle age, smoker. Lung Upper Right lobe mass wt mediastinal lymph nodes. #pulmpath #challengeforme #SCLC #Lungcancer

#Pulmpath #Thoraxicpath Male with lung mass and mediastinal lymphadenopathy.What would be your bet on this one,would you ask for NE markers beside P40 and TTF1? Opinions appreciated 😊🙏


Too late to advertise but in case you join us next week on the Pulmonary Pathology Course in Stockholm, we'll meet on Thursday 🤣🤣I'll be lecturing on the molecular analysis for NSCLC...
https://t.co/SXRP4y7BMo

O brave and wise Tweeples, would you like to try your luck, test your diagnostic eye, and deploy your wisdom on a “no history” case?
#pathology


https://t.co/aoqXDWdaeb
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