Top Tweets for #TumorVesselNormalization

about 2 years ago

#Metformin & #ImmuneCheckpointInhibitor anti-PD-L1 antibody synergistically normalize tumor vessels ⏬Primary tumor growth 🐭4T1 breast cancer ⏫#TumorVesselNormalization ⏬#VascularPermeability 70kD dextran ⏫SM α-actin+ mural cell coverage ⏫VE-cadherin & VCAM-1 & pSTAT1 immunoreactivities Unaltered CD31+ vascular area fraction ⏫PNAd+ high endothelial venule But⏬tumor vessel perfusion 2MD dextran🧐 ⏫CD8+ T cell infiltration ⏬Foxp3+ Treg 👉anti-CD8 or anti-IFNγ Ab abolishes the vascular-normalizing effects of Met/PD-L1 ab Similar TME effects also seen in🐭MO5 melanoma Heiichiro Udono lab @PNASNews 2024 https://t.co/qS5fR9F1mr

$HaoYin20's tweet photo. #Metformin & #ImmuneCheckpointInhibitor anti-PD-L1 antibody synergistically normalize tumor vessels ⏬Primary tumor growth 🐭4T1 breast cancer ⏫#TumorVesselNormalization ⏬#VascularPermeability 70kD dextran ⏫SM α-actin+ mural cell coverage ⏫VE-cadherin & VCAM-1 & pSTAT1 immunoreactivities Unaltered CD31+ vascular area fraction ⏫PNAd+ high endothelial venule But⏬tumor vessel perfusion 2MD dextran🧐 ⏫CD8+ T cell infiltration ⏬Foxp3+ Treg 👉anti-CD8 or anti-IFNγ Ab abolishes the vascular-normalizing effects of Met/PD-L1 ab Similar TME effects also seen in🐭MO5 melanoma Heiichiro Udono lab @PNASNews 2024 https://t.co/qS5fR9F1mr$

Top Tweets for #TumorVesselNormalization

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