#VIPoma - Twitter Hashtag

Dr Strange MCh HPB & GI Surgery @drvipan

4 days ago

📢 PNET Series | Part 4 is Live Now VIPoma: Clinical Presentation, Diagnosis & Management is now available on our YouTube channel. ▶️ Watch here: https://t.co/RhlhzdBcls #PNET #VIPoma #PancreaticNeuroendocrineTumor #SurgicalGastroenterology #HPBSurgery #DrStrangeMCh

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OncoDaily

@oncodaily

6 months ago

When Does an Elevated VIP Level in a Patient With Diarrhea Indicate VIPoma? - @OncoThor https://t.co/1VMffLL1os #Cancer #Medicine #Health #Oncology #OncoDaily #VIPoma #MedX #MedNews #MedEd

oncodaily's tweet photo. When Does an Elevated VIP Level in a Patient With Diarrhea Indicate VIPoma? - @OncoThor

https://t.co/1VMffLL1os

#Cancer #Medicine #Health #Oncology #OncoDaily #VIPoma #MedX #MedNews #MedEd https://t.co/kER9z5ojuA

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News18

@CNNnews18

about 1 year ago

Olivia Williams, known for The Sixth Sense, was diagnosed with VIPoma in 2018. Now an ambassador for Pancreatic Cancer UK, she advocates for early detection tests. #oliviawilliams #VIPoma #PancreaticCancer https://t.co/BkEr18ywAQ

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Dr.Haitham Hamoud | د.هيثم

@hemo_shk

almost 2 years ago

#VIPoma or vipoma (/vɪˈpoʊmə/) is a rare endocrine tumor that overproduces vasoactive intestinal peptide (thus VIP + -oma).The incidence is about 1 per 10,000,000 per year. VIPomas usually (about 90%) originate from the non-β islet cells of the pancreas. They are sometimes associated with multiple endocrine neoplasia type 1. Roughly 50–75% of VIPomas are malignant, but even when they are benign, they are problematic because they tend to cause a specific syndrome: the massive amounts of VIP cause a syndrome of profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria, acidosis, flushing and hypotension (from vasodilation), hypercalcemia, and hyperglycemia. This syndrome is called Verner–Morrison syndrome (VMS), #WDHA syndrome (from watery diarrhea–hypokalemia–achlorhydria), or #pancreatic_cholera_syndrome (PCS). The eponym reflects the physicians who first described the syndrome. #Symptoms_and_signs The major clinical features are prolonged watery diarrhea (fasting stool volume > 750 to 1000 mL/day) and symptoms of hypokalemia and dehydration. Half of the patients have relatively constant diarrhea while the rest have alternating periods of severe and moderate diarrhea. One third have diarrhea < 1yr before diagnosis, but in 25%, diarrhea is present for 5 yr or more before diagnosis. Lethargy, muscle weakness, nausea, vomiting and crampy abdominal pain are frequent symptoms. Hypokalemia and impaired glucose tolerance occur in < 50% of patients. Achlorhydria is also a feature. During attacks of diarrhea, flushing similar to the carcinoid syndrome occur rarely. #Cause The etiology of VIPoma is not currently known. #Diagnosis Besides the clinical picture, fasting VIP plasma level may confirm the diagnosis, and CT scan and somatostatin receptor scintigraphy are used to localise the tumor, which is usually metastatic at presentation. Tests include: ▪Blood chemistry tests (basic or comprehensive metabolic panel) ▪CT scan of the abdomen ▪MRI of the abdomen ▪Stool examination for the cause of diarrhea and electrolyte levels ▪Vasoactive intestinal peptide (VIP) level in the blood #Treatment The first goal of treatment is to correct dehydration. Fluids are often given through a vein (intravenous fluids) to replace fluids lost in diarrhea. The next goal is to slow the diarrhea. Some medications can help control diarrhea. Octreotide, which is a human-made form of the natural hormone somatostatin, blocks the action of VIP. The best chance for a cure is surgery to remove the tumor. If the tumor has not spread to other organs, surgery can often cure the condition. For metastatic disease, peptide receptor radionuclide therapy (PRRT) can be highly effective. This treatment involves attaching a radionuclide (Lutetium-177 or Yttrium-90) to a somatostatin analogue (octreotate or octreotide). This is a novel way to deliver high doses of beta radiation to kill tumours. Some people seem to respond to a combination chemo called capecitabine and temozolomide but there is no report that it totally cured people of VIPoma. #Prognosis Surgery can usually cure VIPomas. However, in one-third to one-half of patients, the tumor has spread by the time of diagnosis and cannot be cured. #MEDHM #MedX @IhabFathiSulima

hemo_shk's tweet photo. #VIPoma or vipoma (/vɪˈpoʊmə/) is a rare endocrine tumor that overproduces vasoactive intestinal peptide (thus VIP + -oma).The incidence is about 1 per 10,000,000 per year. VIPomas usually (about 90%) originate from the non-β islet cells of the pancreas. They are sometimes associated with multiple endocrine neoplasia type 1. Roughly 50–75% of VIPomas are malignant, but even when they are benign, they are problematic because they tend to cause a specific syndrome: the massive amounts of VIP cause a syndrome of profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria, acidosis, flushing and hypotension (from vasodilation), hypercalcemia, and hyperglycemia. This syndrome is called Verner–Morrison syndrome (VMS), #WDHA
syndrome (from watery diarrhea–hypokalemia–achlorhydria), or #pancreatic_cholera_syndrome (PCS). The eponym reflects the physicians who first described the syndrome.

#Symptoms_and_signs
The major clinical features are prolonged watery diarrhea (fasting stool volume > 750 to 1000 mL/day) and symptoms of hypokalemia and dehydration. Half of the patients have relatively constant diarrhea while the rest have alternating periods of severe and moderate diarrhea. One third have diarrhea < 1yr before diagnosis, but in 25%, diarrhea is present for 5 yr or more before diagnosis. Lethargy, muscle weakness, nausea, vomiting and crampy abdominal pain are frequent symptoms. Hypokalemia and impaired glucose tolerance occur in < 50% of patients. Achlorhydria is also a feature. During attacks of diarrhea, flushing similar to the carcinoid syndrome occur rarely.

#Cause
The etiology of VIPoma is not currently known.

#Diagnosis
Besides the clinical picture, fasting VIP plasma level may confirm the diagnosis, and CT scan and somatostatin receptor scintigraphy are used to localise the tumor, which is usually metastatic at presentation.
Tests include:
▪Blood chemistry tests (basic or comprehensive metabolic panel)
▪CT scan of the abdomen
▪MRI of the abdomen
▪Stool examination for the cause of diarrhea and electrolyte levels
▪Vasoactive intestinal peptide (VIP) level in the blood

#Treatment
The first goal of treatment is to correct dehydration. Fluids are often given through a vein (intravenous fluids) to replace fluids lost in diarrhea. The next goal is to slow the diarrhea. Some medications can help control diarrhea. Octreotide, which is a human-made form of the natural hormone somatostatin, blocks the action of VIP.
The best chance for a cure is surgery to remove the tumor. If the tumor has not spread to other organs, surgery can often cure the condition.
For metastatic disease, peptide receptor radionuclide therapy (PRRT) can be highly effective. This treatment involves attaching a radionuclide (Lutetium-177 or Yttrium-90) to a somatostatin analogue (octreotate or octreotide). This is a novel way to deliver high doses of beta radiation to kill tumours. Some people seem to respond to a combination chemo called capecitabine and temozolomide but there is no report that it totally cured people of VIPoma.

#Prognosis
Surgery can usually cure VIPomas. However, in one-third to one-half of patients, the tumor has spread by the time of diagnosis and cannot be cured.
#MEDHM #MedX @IhabFathiSulima

Dr.Haitham Hamoud | د.هيثم

@hemo_shk

almost 2 years ago

A patient with watery diarrhea, hypokalemia, hypochloremia, and acidosis, What is the most likely diagnosis? #MEDHM #MedX #MedTwitter @IhabFathiSulima

hemo_shk's tweet photo. A patient with watery diarrhea, hypokalemia, hypochloremia, and acidosis,

What is the most likely diagnosis?

#MEDHM #MedX #MedTwitter @IhabFathiSulima https://t.co/Rahgn4Xqc7

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H Sh @Hhhash1146519

almost 2 years ago

@hemo_shk @IhabFathiSulima #VIPoma is a rare endocrine tumor that overproduces vasoactive intestinal peptide This syndrome is called Verner–Morrison syndrome (VMS), WDHA syndrome (from watery diarrhea–hypokalemia–achlorhydria),or pancreatic cholera syndrome (PCS). #MedX

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Journal of Brown Hospital Medicine @BrownJHM

about 3 years ago

Hypercalcemia as a presenting feature of VIPoma Read more here: https://t.co/yMaREOWjPe Interested in submitting unique case reports like this? Submit them at https://t.co/rFvzRC86g1 #Medtwitter #MedEd #FOAMed #VIPoma #GItwitter

BrownJHM's tweet photo. Hypercalcemia as a presenting feature of VIPoma

Read more here: https://t.co/yMaREOWjPe

Interested in submitting unique case reports like this? Submit them at https://t.co/rFvzRC86g1

#Medtwitter #MedEd #FOAMed #VIPoma #GItwitter https://t.co/Twu6MxsTqj

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Jock Doc Podcast @jockdocpodcast

over 3 years ago

Listen as Dr. London Smith (.com) and his producer Cameron discuss VIPoma with haunted house guide Carny Smell (@StayClassie). Not so boring! https://t.co/1Qa6iwIEht #VasoactivePeptide #VIPoma #comedy #podcast #hormones #pancreas

jockdocpodcast's tweet photo. Listen as Dr. London Smith (.com) and his producer Cameron discuss VIPoma with haunted house guide Carny Smell (@StayClassie). Not so boring!

https://t.co/1Qa6iwIEht

#VasoactivePeptide #VIPoma #comedy #podcast #hormones #pancreas https://t.co/BOPJHvf595

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Paul McKenzie @MrSmileEsq

about 5 years ago · Exeter

Very disappointing that @reallorraine @lorraine show had a tagline of @PanCAN throughout her interview with Olivia Williams. She had a #vipoma which is a rare version of @Neuroendocrine_ cancer. We could do with more exposure of NET'S

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Dr.Hàsh @haseenmmahim

about 5 years ago

@meta_morphopsia #Vipoma 😛

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CU Anschutz Endocrinology @CUEndocrinology

over 5 years ago

#NETCancerDay NETs form from neuroendocrine cells anywhere in body w capacity to release hormones in response to neural stimuli. Many are non-functional; those making hormones cause extra high morbidity. #insulinoma #pheo #para #VIPoma #gastrinoma #ectopicACTH #ectopicPTHrP

CUEndocrinology's tweet photo. #NETCancerDay
NETs form from neuroendocrine cells anywhere in body w capacity to release hormones in response to neural stimuli. Many are non-functional; those making hormones cause extra high morbidity. #insulinoma #pheo #para #VIPoma #gastrinoma #ectopicACTH #ectopicPTHrP https://t.co/Ppc3yPXNXa

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C🧵R🧲J🩸N😷 @CirujanoGZ

almost 6 years ago

El #VIPoma (VIP, péptido intestinal vasoactivo) da Verner-Morrison o Síndrome de WDHA: Diarrea acuosa, hipokalemia, aclorhidria (#cólera pancreático). Algunos pacientes pueden tener flushing (20%) #Glucagonoma: diabetes, dermatitis, deep vein thrombosis and #depression...sigue👇🏻

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Neil Walsh @NeilWalsh_UN

over 6 years ago

Niche audience for this one but have any of you had #Octreotide #Sandostatin 100ug SC injections? Did you have horrible side effects? #nausea #steatorrhea #chills #fatigue #sweats horrendous #headache? 🙏 #BowelCancer #ColorectalCancer #Carcinoid #NeuroEndocrine #VIPoma

NeilWalsh_UN's tweet photo. Niche audience for this one but have any of you had #Octreotide #Sandostatin 100ug SC injections? Did you have horrible side effects? #nausea #steatorrhea #chills #fatigue #sweats horrendous #headache? 🙏

#BowelCancer #ColorectalCancer #Carcinoid #NeuroEndocrine #VIPoma https://t.co/88wfPXUIZX

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Ronny Allan 💙also on Bluesky

@RonnyAllan1

over 6 years ago

Olivia Williams – #NeuroendocrineCancer ( #VIPoma ) @NETCancerBlog #OliviaWilliams https://t.co/bafsy9v2ee

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Ronny Allan 💙also on Bluesky

@RonnyAllan1

over 6 years ago

I just wonder why actress Olivia Williams is not an ambassador for the @netpatientfound, the cancer she actually has. #neuroendocrinecancer #VIPoma https://t.co/CWrMuuc6Ne

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