Top Tweets for #aaiso
They’ve changed the description of Angioedema causes as:
Mast-cell induced
Bradykinin induced
#AAISO
Was previously called histamine-induced but many other mediators are released from mast cells.
I’m at #AAISO Ontario Allergy Update. An interesting point about patients with CSU (chronic spontaneous urticaria) is that they are more likely to have allergic diseases such as: allergic rhinitis and asthma than the general population.
Dupilumab is approved in Canada for mod-severe atopic dermatitis. Can significantly reduce AD symptoms, especially itch, but is not covered by all drug plans making it difficult for patients to receive it in English-speaking Canada #AAISO Conjunctivitis is the main side effect
Crisaborale is a new topical treatment for atopic dermatitis that is non-steroidal. It does not appear to be *more* effective than other topical treatments but it can be used on sensitive areas and had fewer local irritation effects than calcineurin inhibitors #AAISO
Persistence predictors of atopic dermatitis:
Female
Family income <$50k/year
Non-white race (mostly black)
History of atopy
Maternal eczema
Maternal asthma
Paternal asthma
*Asthma age 7
#AAISO
Q: Will people outgrow eczema?
A: Recent study showed truly *symptom-free” at 20%. However a meta-analysis birth cohort study showed 80% outgrew it #AAISO Maybe issue with when study started ie eczema that starts very early maybe better outgrown
Last talk is on Atopic Dermatitis by Dr Aaron Drucker from Toronto #AAISO
Trauma
Infection
Surgery
Dental work
Estrogen &
ACE inhibitors can all predispose to acute attacks of HAE #AAISO
If there is bowel involvement with the lesions of angioedema it’s quite likely to be Type 1 HAE #AAISO
@IgECPD @walkforandrea I wondered if you would be tweeting #AAISO ! I had @AllergyRes duties today so couldn't make it - great looking line up though!!
There does appear to be a linkage (in some EoE patients) between their environmental allergies and swallowing symptoms. They have a ‘seasonality’ to their EoE symptoms #AAISO
Asthma is associated with a 78% risk for cognitive impairment.
The risk of dementia/Alzheimer’s disease is more than double in patients with asthma.
The risk scales upward with the frequency of asthma exacerbations #AAISO
The anterior cingulate cortex is a region of the brain that helps to judge pain and feelings of conflict in the body #AAISO
There is an area of the brain called the anterior cingulate cortex that has different levels of activation depending on whether a methacholine or an antigen challenge takes place. The greater the change in lung function, the greater the change #AAISO
Eosinophils are noted to rise in study of students taking examinations. Not only around the time of the exam, but also for the next week #AAISO It seemed to make them more susceptible to allergic asthma triggers
Maternal anxiety/depression is a risk factor for asthma in offspring.
Increased rates of depression and anxiety are noted in asthmatics.
Increased anxiety is a risk factor for asthma exacerbations #AAISO
Looking forward to next talk on links between stress and asthma #AAISO Once again, Dr Bill Busse from Madison, WI
There are a half-dozen case reports of food avoidance suggested as a treatment for EoE which resulted in IgE mediated (systemic) reactions upon re-introduction #AAISO
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