Top Tweets for #bafcomplex
Excited to see our collaborative work with @Oser_Lab @DanaFarber @DanaFarberNews on #SCLC #lungcancer out in @Cancer_Cell, identifying chemically targetable #BAFcomplex chromatin regulatory dependencies and providing foundation for new clinical studies for this aggressive cancer.
Online Now: Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer https://t.co/c3vWNzt3YL
Kudos to Megan Mcnerney, MD PhD and her team on publishing an excellent research article in @CellReports demonstrating #CUX1 regulation of hematopoietic stem cells via #BAFComplex.
@UCCancerCenter @UCPathology @UChicagoCCB
https://t.co/OZD1C2pJLk
Exciting new results from our @kadochlab with the Politi lab at Yale highlighting the utility of mSWI/SNF #BAFcomplex ATPase inhibitors in reversing kinase inhibitor #drugresistance in #EGFR-mutant #lung #cancers. Congrats to the team on this timely and impactful study!
Online Now: Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer https://t.co/9vEIvTo1nK
Exciting new work highlighting the utility of #mSWISNF #BAFcomplex ATPase inhibitors in reversing kinase inhibitor resistance in EGFR-mutant lung cancers @Cancer_Cell ! A great collaboration with @politikaterina lab at @YaleCancer ! Congrats to @fdemiguelsdp , @claudiagentile_ !
Online Now: Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer https://t.co/9vEIvTo1nK
Congratulations to @FreddyMValencia and @akshaysci on their newest study, just published in @NatureGenet ! Beautiful analysis highlighting that #SWISNF /#BAFcomplex genes are the most frequently perturbed gene classes in #neurodevelopmental disorders.
https://t.co/ldB3O9I7SM
Another great story from Kadoch lab and @iannisaifantis1 lab @CKadoch “ targeting #BAFcomplex for T cell maintenance/exhaustion” another step towards improving anti tumor therapies 👏🏻👏🏻 read for today
Happy to see our work on #Tcells #CART out today in @MolecularCell! Great collaboration with my good friend and colleague, @iannisaifantis1 as we worked out the role for #BAFcomplexes in mediating T cell #exhaustion. https://t.co/Nm79Wz4wFw
Congrats to @ajinkyapatil00 from my @kadochlab @DanaFarber @harvardmed @HHMINEWS and @JinWei0911 from the @WilenLab @YaleMed on this exciting new study! #chromatin #viruses #sarscov2 #COVID19 #BAFcomplex #inhibition
Researcher @Ckadoch finds that a new class of oral drugs can inhibit a wide range of SARS-CoV-2 variants.
💻 https://t.co/65XV0620Yw
Big congratulations to @ajinkyapatil00 from our @kadochlab and @JinWei0911 from the @WilenLab @YaleSOM on their terrific new study out today in @NatureGenet -- a fantastic collaboration! @CKadoch @DanaFarberNews @harvardmed #sarscov2 #virus #chromatin #BAFcomplex
🎆 ONLINE TODAY @NatureGenet
📰 Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection
👫 @WilenLab @CKadoch @kadochlab @JinWei0911
@ajinkyapatil00 and team
👇🏻
https://t.co/Z7YS8CU999
@WhetstineLab @NVijayvergiaMD @FoxChaseCancer Up Next @foghorntx talking #ChromatinRemodelers #BAFcomplex
Thanks for being part of #CEI2023Symp
@CKadoch
🚨#phdpositions available with @luck_katja
1️⃣ Role of #BAFcomplex in #GenomeStability ➡https://t.co/NRMjVqHTwe
2️⃣Protein degradation in #NuclearCondensates ➡https://t.co/cF85jUI7sd
Apply by 19 Nov https://t.co/x2ImF2Eljf
#proteomics #Bioinformatics
#Biochemistry #Biophysics
Congratulations to @kadochlab members @proodolph, Clayton Collings, and our many collaborators on this exciting new study focused on the mechanism of an aggressive #meningioma subtype! #cancer #BAFcomplex #chromatin #ncBAF #BRD9
Congrats to @proodolph, Clayton Collings and all co-authors on this recent publication in @NatureGenet! #cBAF compromise via SMARCE1 loss in clear cell #meningioma (CCM) -->increased assembly and function of #ncBAF complexes, leading to CCM-specific oncogenic gene expression.1/2
What is the prenatal phenotype of Coffin-Siris syndrome? #ARID1A #BAFComplex #Fetal #SMARCA4 #SMARCB1 https://t.co/h74Q5HN5bb
Just released the results of an incredibly fruitful collaboration with experts around the world: "BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma"
#rhabdomyosarcoma #BAFComplex #PAX3FOXO1
https://t.co/RcMywNDhQg
In every 5th cancer there's a mutation found in 1 of the #BAFcomplex genes. In their new @NatureGenet paper CeMM PI Stefan Kubicek’s lab revealed how quickly changes in this complex' genes influence the accessibility of DNA🧬 & the information stored in it https://t.co/q5J99CPOmR
There’s a new BAF complex in town. Say hello to non-canonical BAF. Thanks for the discovery @CKadoch! #BAFcomplex #chromatinremodeling #ADCR https://t.co/w2MoJeQCyn
I had the great honour to do the visualisation for the Chemical #Epigenetics Lab @CeMM_News, their breakthrough research has been published @NatureGenet, @oeaw covers their findings concerning #Cancer and #BAFComplex-mutations in more detail (german) https://t.co/HAiz9lB19S
Watch the @CeMM_News video about the @NatureGenet paper of Sandra Schick & Stefan Kubicek in collaboration with @Boehringer. BAFfling cancer growth strategies: new targets for chromatin remodeling mutations identified. #Epigenetics #BAFComplex #Cancer https://t.co/3csc5Y8T52
Brg1 (D1Q7F) Rabbit mAb #ChIPseq #AbValidated #antibody. #ChromatinRegulation #TumorSuppressor #BAFcomplex https://t.co/hdAaWLBtW5
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