Top Tweets for #complementactivation
🩸🚀Today’s clinical questions!
Swipe to see the answers and explanations.
#PNH #ParoxysmalNocturnalHemoglobinuria #Eculizumab #Ravulizumab #C5Inhibition #ComplementSystem #BreakthroughHemolysis #PKBreakthrough #Pregnancy #ComplementActivation #DrugClearance #PlasmaVolume #MaternalHealth #ThrombosisRisk #Hematology #HemeOnc #ClinicalHematology #MedicalEducation #MedEd #HEMEHUB

New Proteomic Insights into MPN Thrombosis from @blanca_demoner and Team
@CarrerasIJC
https://t.co/0rG7l5TPqi
#ComplementActivation #Health #Hematology #MPN #Hemostasis #Thrombosis #HemostasisToday #MedX #JAK2V617F #TranslationalOncology #MPNThrombosis #JosepCarrerasLeukaemiaResearchInstitute #Medicine #MyeloproliferativeNeoplasms #ProteomicProfiling #MedEd

Complement Activation Is the Hallmark of Atypical HUS - Eric Goffin
https://t.co/l1ewlt8uYz
#AHUS #AtypicalHemolyticUremicSyndrome #MedEd #ComplementActivation #Hematology #Hemolysis #HemostasisToday #KidneyFailure #Medicine #MedX #Nephrology #Thrombosis

Novel insights into #APS extend beyond #Thrombosis to NETosis, #ComplementActivation and #MicrobiomeDysbiosis. The 2023 ACR/EULAR criteria refine diagnosis. Adjunctive therapies such as HCQ, rituximab and eculizumab show therapeutic potential: https://t.co/a5GX6RjkSx #MedTwitter

"It could make someone useless for a year+" ~ @StatisticUrban . Yep! 13 years + of #MEcfs disability for me stemming from #malaria and residual #Hemozoin. Elevated #ComplementC7 #ComplementActivation #TLR3 #MGUS
If you've never had malaria, it's awful. It infected over 1 million per year, caused widespread anaemia, miscarriage, and childhood death. The disease could last for months, with multiple recurrences, and led to chronic undernourishment
It could make someone useless for a year+
The connection between #SARSCoV2 and #PNH is significant, with infection potentially unmasking or #exacerbating PNH through #complementActivation, and vaccination, particularly mRNA types, posing a risk of hemolytic flares.
https://t.co/jm5GcRq8wU
Study highlights the role of #ComplementActivation in #APS, linking elevated C3a, C4a, C5a, & C5b-9 levels to more severe cases, including recurrent #thrombosis & CAPS. Findings suggest complement inhibitors like eculizumab may offer new treatment options: https://t.co/XDdxdsHNRk

Study explores #ComplementActivation in #AntiphospholipidSyndrome, aiming to clarify its role in thrombotic recurrences and disease severity. Mechanistic studies seek markers and evaluate complement inhibition: https://t.co/NyMDuTRvD1
New #openaccess laboratory study. Does #dexmedetomidine help prevent cognitive decline induced by sleep loss via #complement? #sleepdeprivation #complementactivation #anaesthesia #criticalcare
https://t.co/T4b6tuYCTW

Interesting article from Pfizer
🔬 Researchers investigate complement activation by AAV9 gene therapy vectors in human serum samples
🔍Scientist used NAb, TAb and complement assays to understand AAV9 complement activation.
#AAV #GeneTherapy #ComplementActivation #Immunology 1/2

Why do so many pancreas transplants fail due to thrombi? This study shows increased thromboinflammation and association with #complementactivation in pancreas transplanted patients (especially those who only get a pancreas and not a kidney) https://t.co/N1LBFhs6pl
Recently the complement system has attracted a considerable amount of interest in #COVID19 patients. In severe #COVID cases, #ComplementActivation and associated inflammation have been linked to disease propagation.
Read more about this on our blog:
🔗: https://t.co/p22ZmOPWNZ
A marker of particular interest concerning the complement system is the #C4d fragment, which acts as a sensitive and long-lived marker of #ComplementActivation.
Click the link below to learn more about our range of C4d antibodies:
🔗: https://t.co/DfkzZAx2kM
Open🔓Access Paper📖
A naturally hypersensitive #porcine model may help understand the mechanism of #Covid19 #mrnavaccine-induced rare (pseudo) allergic reactions: #complementactivation as a possible contributing factor.
https://t.co/Ys5ooYd7u7
@semmelweishu @unimiskolc

Teaching #ComplementActivation in #Immunology for our #MLT students @RoseState. These visuals were pretty cool @ASCLS @ASCP_Chicago #MedLabScientist #Lab4Life

Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes.
| Tatsuhiro Ishida, Tokushima University |
#liposome #pegylation #ComplementActivation
[50 days' free access]
https://t.co/0wDm26DItp
Look out for possible #CovidVaccines #Mrna #AnaphylactoidReaction
#Complement #complementactivation
With #Pfizervaccine $PFE
#UKvaccine
#immunology
"a defence system turning offensive" https://t.co/qZvPQ7ywbS
In their recent study, Pandey et al sought to understand the role of IgM and IgG and #complementactivation by anti-A on #extravascularhemolysis. Read more: https://t.co/e8Dy7hiMGE
#ISBTScience

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