Top Tweets for #ePhys
Danger sharpens your inner compass! π§π
Using #ephys in head-fixed #awakemice, Preston-Ferrer lab @uni_tue shows alerting sounds boost head direction coding in the anterior thalamus πππ
https://t.co/a5xpMEUEQS
One shape, many volumes!π
Using #ephys & #optogenetics in #awakemice, Hsiao-Chen Liu & Shih-Chieh Lin show one-sided Npr3 activation recruits the full bilateral basal forebrain burst, encoding reward prediction πππ
https://t.co/PZJfK4u2ck
Check out @voroslakos sharing his vast expertise on high-density #ephys with @neuronexustech last month. 5 key takeaways πππππ
π§ Watch the full episode with Mihaly Voroslakos about turning massive electrophysiology datasets into meaningful neuroscience.
π§ Watch on YouTube- https://t.co/xaen5KoQiL
and Spotify- https://t.co/XV3joxvrYJ
#Electrophysiology #Neuroscience #DataScience #NeuroNexus
Standing still, yet mapping π§
@n_sartorato @ABurgalossi & team use #ephys in head-fixed #awakemice on a treadmill to show CA1 place cells keep encoding location during immobility, driven by a behaviorally-modulated subset of cells gated by arousal ππ
https://t.co/xr2O0sB1BX
Astrocyte biology is back in the spotlight of #epilepsy research. New preprint from @LabWykes: knocking out a single astrocyte potassium channel in the hippocampus is enough to trigger spontaneous seizures - & make them worse. #ephys #epilepsy #awakemice https://t.co/XJIJMs2TU9
Ramping activity and time!β±οΈ
Using #ephys in freely-moving & head-fixed #awakemice in the #MobileHomeCage, @aldridge_lab shows prefrontal neuronal ramping and ~4 Hz theta activity may be features of interval timing rather than motor programs πππ
https://t.co/iJjo1gG4ce
Delta never sleeps! π΄π§
Using #ephys in juvenile rats in the #MobileHomeCage, Ahmad, Sokoloff & Blumberg show that cortex-PZ delta synchrony persists through sleep deprivation & hypercapniaπππ
https://t.co/DODsf9QPYF
Motor cortex is selectively recruited by context!π§
Using #ephys & whisker stimulation in #awakemice, @SachdevRobert lab shows that vM1 neurons respond strongly to passive whisker stimulation but are barely engaged during active goal-directed whisking ππ
https://t.co/6k8vZ3EBm3
Short-term plasticity, long-term consequences?π€
Using #ephys in #awakemice, @CathMarneffe et al. show that deleting Syt7 at Mf synapses suppresses short-term presynaptic facilitation, disrupts CA3 co-activity & impairs pattern completion in memory tasks!
https://t.co/bbylKHoa3L
How cool is this? βοΈ
wS1 in neonatal mice responds to orofacial cooling from the first postnatal week!
Using #Invigilo #widefield & #ephys, Matarazzo lab @Inserm, @AnastasiaLudwig & @RNeurolab reveal thermal processing disruptions in an autism modelππ
https://t.co/xsvH4jJx6X
Cracking the code of cortical rhythms β‘οΈπ§
Using #ephys and phase-targeted optogenetics in #awakemice, @ASharott,Β @cjstagg & teamΒ show that stimulating excitatory vs inhibitory neurons modulates cortical theta power in a phase-dependent manner! ππ
https://t.co/gAQ2eQm4OX
Preprint from my lab @YalePharm uncovers the molecular mechanisms of uncoupling nociceptive and neurotrophic TrkA signaling using #singleMolecule #microscopy, #cryoEM, #ephys, #signaling, offering a clear blueprint to target this much sought-after pathway! https://t.co/tpkHpoW14d
First ephys recordings in my own lab!!!π₯ΉCanβt believe itβs happening. The first of many to come! Letβs gooo!
#NewPI #neuroscience #ephys
Planning to record LTP or LTD in acute brain slices with whole-cell patch clamp? Give my latest article a look! https://t.co/RILfkUKYW0 #plasticity #patchclamp #electrophysiology #ephys π¬πͺβ‘οΈ
How do neurons "learn"?
By strengthening (LTP) or weakening (LTD) their synapses. In this article, @emily_winson, @GrubbLab explains how to record these fundamental processes using whole-cell #patchclamp. Read the guide here: https://t.co/WfkbhN2IcR
"Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?" in Advanced Science, link to the paper: https://t.co/J5yVnm7Lw7... #neurotechnology #neuralinterfaces #iBCI #neuralink #invasive #ephys #clinical #electrode #sysneuro #highdensity 5/5
Same gadget to record and stimulate brain activity? π§ β‘οΈNew research from the Garrido and GuimerΓ -Brunet labs @icn2nano & @LabWykes shows how graphene tech enables both with a single neural interfaceΒ #MobileHomeCage #ephysΒ Β https://t.co/KF9UxqnXg9
Going beyond the brain? Try fixing the spine!
Our spine plates tailored-made for the #MobileHomeCage enable stable fixation for awake #twophoton imaging or #ephys recordings.
More info: https://t.co/tWU6Ga3ezV
Gamma oscillations in the prefrontal cortex emerge lateβwhy? The @HanganuOpatzLab shows that PV+ interneurons drive gamma in adolescence, replacing SOM+-driven beta. This shift strengthens cross-hemispheric synchrony. #MobileHomeCage #ephys #optogenetics https://t.co/Kum6CqarlT
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