Top Tweets for #ecd16
🌟 | Naci Ünüvar’s last 2 weeks...
• EURO U17 Champion 🏆
• EURO U17’s youngest goalscorer in a final 🎖
• Scored 2 crucial goals in Ajax U19’s 2-1-win over Sparta 🤩
• Signed his first contract ✔️
• Abdelhak Nouri Award Winner 🌟
• U19 Cup Winner 🏆
• U19 Champions 🏆
@notthatdrjones: RT #ecd16 and #epigenetics folks - awesome collaborators are looking for a talented PDF/RA in exp… https://t.co/n6qOzBl55m
.@RoliRoberts and talking of gender in genomics, #PLOSBiology have just published https://t.co/dVCLdudYyj & https://t.co/uyrARF1bMX #ECD16
Thanks to prog committee, speakers, poster presentors and all participants for making #ECD16 such a great sucess - see you all next year!
Thanks @GenomeBiology @Magda_Skipper @notthatdrjones @PLOSBiology + for #ECD16 tweets. Quick abstract word cloud: Methylation at the top 1/2
Congrats to Emily for winning the best short talk award! Great end to a great conference! #ecd16
Congratulations to Matthias Thurner for winning the #ECD16 poster prize @RDMOxford @markmccarthyoxf @HumanGeneticsOx
Congrats to all the prizewinners at #ECD16 very well deserved! And thus ends this year's conf!Been a fantastic showcase of excellent science
#ECD16 - R Kempfer: GAM (Genome architecture mapping) new method for exploring relationship between 3D genome finding & gene expression
Kempfer: a cool cryosectioning-based method to map 3D interactions - GAM - applied to rare cell types like DOPA neurons #ecd16
Take home message from Spitz: lots of opportunities 4 genetic variation to disrupt 3D interactions, change expression, cause disease #ECD16
#ECD16 Genome Architecture Mapping - an approach to identify chromatin contacts genome-wide, Rieke Kempfer.
Spitz: TADs may function to organise transcription: bring enhancers to the 'right' promoters; loss of TADs -> more ncRNAs/ectopic RNA #ecd16
Spitz: 2 types of 3D organisation - gene expression-dependent (cohesin-independent) "compartments" and cohesin-dependent TADs #ecd16
Spitz: epigenetic modifications outside promoters and enhancers may modulate 3D conformation of the genome #ecd16
"Super-enhancer" near MYC is actually cluster of enhancers, each active in diff haematopoietic lineage, not a super-enhancer - Spitz #ECD16
Francois Spitz #ECD16: within a TAD, distance between enhancer & target gene doesn't matter much. Abolish TAD - distance becomes crucial
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