Top Tweets for #epitopeediting
Epitope Editing Strategy Could Enable Less Toxic Stem Cell Transplants
Ability to avoid pretransplant chemotherapy could open up #stemcelltransplants for patients who might otherwise be too sick or too high risk
@Genovese_Lab @DanaFarber
#epitopeediting
https://t.co/fjGuztLrNE
Innovativa ricerca al @DFBC_PedCare.
Con l'#EpitopeEditing, le CAR-T possono colpire solo le cellule di #leucemia mieloide acuta, evitando danni alle cellule sane.
Ce ne parla il ricercatore @CasiratiG, autore di una interessante pubblicazione su Nature.
https://t.co/q7CNcBFwmv
#EpitopeEditing e #CRISPR per rendere le cellule tumorali "riconoscibili" dalle CAR-T.
Uno studio dei ricercatori della @PennMedicine, con Carl June, il padre delle CAR-T, spiega la filosofia dietro questa procedura promettente.
#Tumori
https://t.co/na9QJwUkre
#epitopeediting #epitope Engineering the “missing” piece in #geneediting and #immunotherapy 2.0 @CasiratiG 💫
I'm thrilled to announce that our work, 'Epitope Editing Enables Targeted Immunotherapy of Acute Myeloid Leukemia,' is out today in Nature journal!
Link: https://t.co/nC05EjWMPw
doi: https://t.co/t8CWop6Z4k
@wellhausrn @PennMedicine @Penn 12/By using #CRISPR #BaseEditing technology - #EpitopeEditing creates a #cancer-specific antigen in all residual host hematopoietic cells thus proving its potential as a versatile therapeutic #technology with future applications even beyond CAR-T #cells for blood #cancers.
3/@wellhausrn and @PennMedicine research team mapped the amino acid which are required for binding by anti-CD45 CAR-T cells and they did so by using alanine mutagenesis in order to identify which target will be most suited for #EpitopeEditing👇
1/A new & promising platform was presented at #ASGCT2023 by @PennMedicine’s @wellhausrn - #EpitopeEditing. By using #BaseEditing #EpitopeEditing aims to shield hematopoietic cells from CD45-directed #immunetherapy without the loss of CD45 protein function. #BioTech #CRISPR $BEAM
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