Top Tweets for #igaN
IgA Nephropathy #IgAN: Pathophysiology and Mechanistic Targets π― of Potential Novel Therapies from @goKDIGO
#Nephpearls
π https://t.co/Eb3BaeBzUh
@VertexPharma has joined the REIGNITE Study as a funding collaborator. REIGNITE is an international registry aiming to enroll 6,000+ patients with biopsy-confirmed IgA nephropathy to close real-world evidence gaps in #IgAN. Learn more: https://t.co/berdCBYvoP
IgAN+ just won Gold.
Our app for people living with IgAN and their care partners earned Gold for Health & Wellness and Silver for Best User Experience at the 2026 W3 Awards.
Built with our community and AGP.
https://t.co/j42X1abPJf
#Igan #Iganplusapp #Iganephropathy
Treatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgA nephropathy #IgAN, leaving patients at risk of ESKD ca. 2026 from @DrAnjayRastogi @asnpublications
#Nephpearls
π These findings underscore the need for disease-modifying therapies capable of effectively preserving kidney function, particularly in this predominantly young patient population
π https://t.co/X5IwDS04n9
1/4 eGFR slope is now a common outcome in #IgAN trials and KDIGO has proposed a treatment target of <1 mL/min/1.73mΒ²/year decline.
We asked: could we predict a patientβs future eGFR slope to identify risk of progression earlier?β¨https://t.co/NF8cENBEzb
@NavTangri @SevenOaksCDIC
Some projects feel special from the start βοΈSo grateful to be working with Dr. Glassock @GlassockJ on an exciting initiative #GlomerularDisease. Can't wait to build something meaningful together ππ»
#RareKidneyDisease #IgAN
Adults with #IgAN are at greater risk of adverse kidney outcomes versus nonglomerular CKD and substantially higher risks of heart failure and death compared with no CKD ca. 2026 from @KIReports
#Nephpearls #RKDSummit
ππΌ https://t.co/ZcpIXW2TvQ
Dipstick hemoglobinuria is associated with histologic markers of active disease in #IgAN and may provide clinically relevant information to complement current assessment of disease activity in #IgAN ca. 2026 from @Kidney_Int @LadanZand @fervenzaf
#Nephpearls #RKDSummit
ππΌ https://t.co/NtxaDs0YtT
Microscopic hematuria as a risk factor for #IgAN progression: considering this biomarker in selecting and monitoring patients ca. 2023 from @LadanZand @fervenzaf
#Nephpearls #RKDSummit
ππΌ https://t.co/2uWJ8miYNV
π¨ Latest news in #IgAN!
Sefaxersen achieved statistically significant and clinically meaningful reductions in proteinuria vs placebo at week 37 in the phase III IMAgINATION study.
By inhibiting hepatic production of complement factor B, sefaxersen targets a key driver of complement activation in IgA nephropathy π§¬
#Nephrology #Complement #IgAN #GlomerularDiseases #ClinicalTrials
π https://t.co/5wq000CYBG
Delphi panels are a powerful way to capture expert consensus; though they take real time, #discipline & #teamwork to do right. Proud of our team on this one βοΈπ₯
#IgAN is evolving fast; another Delphi post-#ASN feels inevitable π
#RareKidneyDisease #RKD #GlomerularDiseases
π https://t.co/Q7aiTlOrno
@AKronbichler @kidneybiz @BradRovin @SWadhwaniMD @jradnephro @Madanef30 βοΈπ₯ππ»@GlomCon
Dr. Rhee @ConnieMRhee presented important data on #IgAN
Also look at what it comes up when you google her name!! βMaking history as the first female EIC @JASN_News #CJASN π π₯
A combination of Iptacopan+MMF + low dose steroids @UpToDate for patients with severe disease with crescents and progression @GlassockJ
#IgAN #RareKidneydisease
Dr. Zuckerman @JZRenalPath fantastic talk on #IgAN pathology.
Inflammatory/hypercellularity within the segmental sclerosing lesion could be a good prognostic factorπ₯
βMost patients who makes it to your office will have lost half of their nephrons already.β- Prof Jonathan Barrett addressing the audience at #WUSTLNeph Glom Conference 2026 on #IgAN @Ting2li
Think of #IgAN pathogenesis as a result of 4 hits - note that hit 0-3 appear to be B cell mediated - Dr Rovin @ting2li #WUSTLNeph
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