Top Tweets for #knowtopass
Blood smear showing stomatocytes (coffee-bean/slit-like pallor)
Found in Rh null disease (absolute ❌D, C, E antigens), mutated RHAG (Rh Associated Glycoprotein) gene (transporter for the antigens to the RBC membrane)
>Chronic hemolytic anemia
#KnowToPass #PathBoards #PathTwitter
🔴Goblet cell adenocarcinoma of distal appendix
Note expansion of appendix wall, goblet cell morphology (cell groups dissect through muscularis propria)
Grade according to tubular pattern (G1 >75%; G2 50-75%; G3 <50%)
🧬WNT pathway, ARID1/2
#KnowToPass #PathBoards #PathTwitter
ABO typing
Checking pt's RBC antigens & plasma Abs, via agglutination
‣Forward typing: use pt RBCs
‣Reverse typing: use pt plasma
Concordance has to be demonstrated & a discrepancy must be investigated before the ABO type can be interpreted #KnowToPass #PathBoards #PathTwitter
Breast-collagenous spherulosis
🟢Intraductal deposits of acellular basement membrane material (PAS+). Common w/ sclerosis, papilloma, UDH
📌🛑Myoeps are often compressed (! not DCIS/adenoid cystic carcinoma)
#KnowToPass OR as @smlungpathguy says #KnowOrFail 💀😬 #PathTwitter
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