Ever wondered where H&E came from & how it works?
•Combo: haematoxylin & eosin; first used 145 yrs ago
•H: natural dye of logwood tree native to Central America; oxidized product hematein & mordant: ➕charged metallic ions: Al turns blue 1/
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What’s the diagnosis of this breast lesion? 🤔🔬
Poll in comments 👇
Answer reveal on Monday 🔮
📅 Specialty Conference 25 | Oct 11 | 6–8 PM
📍#IAP2026 | Fukuoka 🇯🇵
👨🏫 “Problems in Breast Pathology” Revisited
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A ser(i)ous identity crisis: Metastatic breast carcinoma in pleural fluid
Malignant epithelial cells distinct from mesos (look for clusters, loss of polarity, nuclear pleomorphism ±nucleoli)
Intracytoplasmic vacuoles or mucin
Origin workup: GCDFP-15, mammaglobin, ER
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A middle-aged female patient with a brain lesion, known to be medically free.
In this case, what should be our initial thoughts? And what is the top differential diagnosis?
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