Top Tweets for #pLGG
Weirdly bullish on $CATE ๐
this one's close.
help push $CATE over the line.
https://t.co/7cYivB1L2E
#plgg https://t.co/jgvqZc7IpX
Tovorafenib continues to reshape care for BRAF-altered r/r pediatric LGG. Post-hoc FIREFLY-1 data show largely low-grade, manageable rashes and flexible oral dosing, supporting broader access to targeted therapy. ๐
Read more: https://t.co/DY1Ot1GDrW
#pLGG #TargetedTherapy
Updated FIREFLY-1 results highlight sustained benefit with tovorafenib in pediatric LGG, including extended TTNT and encouraging retreatment activity as follow-up matures. ๐ง
See the analysis: https://t.co/mqHMOBpHTg
#pLGG #CancerTrials
๐ฐ: Dietvorst et al. conducted a retrospective analysis across four European tumor registries to evaluate the role of intraoperative ultrasound and MRI on achieving complete resection in pediatric low grade gliomas. #ChildsNervSyst #pLGG
๐: https://t.co/sjh4cyYhT6
I'm looking to bring the following teams into @PhantomLegionGG:
๐ชCOD
โ๏ธGOW
๐ฅHALO
๐ธOVERWATCH
#esports #PLGG #lft
Congratulations to @drsam and the team @DayOneBio on this incredible impact for #pLGG patients and their families!
We are proud to share the accelerated approval by the US FDA of the first targeted medicine for the treatment of patients with relapsed or refractory pediatric low-grade glioma (#pLGG) with a BRAF fusion or rearrangement, or BRAF V600 mutation. Learn more: https://t.co/7nmHsiyhDD
We are proud to share the accelerated approval by the US FDA of the first targeted medicine for the treatment of patients with relapsed or refractory pediatric low-grade glioma (#pLGG) with a BRAF fusion or rearrangement, or BRAF V600 mutation. Learn more: https://t.co/7nmHsiyhDD
Great to see that tovorafenib, a RAF inhibitor, has been granted FDA accelerated approval for treatment of pediatric r/r BRAF+ low-grade #glioma. Approval was based on the phase 2 FIREFLY-1 trial, which we published last year in @NatureMedicine! #pLGG https://t.co/Zy2Bc506kd
BREAKING: @US_FDA Grants Accelerated Approval to Tovorafenib for Pediatric Relapsed/Refractory BRAF+ Low-Grade Glioma https://t.co/u8bTpYmHuc
We are proud to share the accelerated approval by the US FDA of the first targeted medicine for the treatment of patients with relapsed or refractory pediatric low-grade glioma (#pLGG) with a BRAF fusion or rearrangement, or BRAF V600 mutation. Learn more: https://t.co/7nmHsiyhDD
Mollyโs advice for others going through a pediatric low-grade glioma journey is to keep a list of questions to ask the doctor โ even the small things. To hear more stories from people living with #pLGG & tips for navigating a challenging diagnosis, visit: https://t.co/6o8nCTqGkz
#SJ901, a @stjuderesearch study using a Mirdametnib to treat children & AYAs with low-grade glioma, is enrolling patients in one of 3 treatment cohorts basedย ย on tumor status & history of MEK inhibitor exposure. Learn more: https://t.co/MKDj3rBEc1 #PLGG @DrGilesRobinson
Selt et al. present a novel protocol for generating patient-derived pilocytic astrocytoma cell lines using SV40-TAg to circumvent oncogene-induced senescence. #pLGG @TillMilde @DKFZ @HiTZ_HD @ahmedeldamaty
https://t.co/6MUXaajEuN
In a phase 2 trial, the oral type II RAF inhibitor #tovorafenib exhibited an overall response rate of 67% in patients with #BRAF-altered relapsed/refractory pediatric low-grade #glioma @ChildrensNatl @DayOneBio @drsam #pLGG #btsm #pediatriccancer https://t.co/JitC1Wz8ga
In a phase 2 trial, the oral type II RAF inhibitor #tovorafenib exhibited an overall response rate of 67% in patients with #BRAF-altered relapsed/refractory pediatric low-grade #glioma @ChildrensNatl @DayOneBio @drsam #pLGG #btsm #pediatriccancer https://t.co/JitC1Wz8ga
Discovering that your child has pediatric low-grade glioma (#pLGG) is very difficult to hear. Our discussion guide can help start an informed discussion with your healthcare team about treatment planning. Download here: https://t.co/5YnLjrTEgY
Awesome talk by rising star Anna Zapaishchykova on survival risk modeling of #pLGG at #pedSNO2023 @NeuroOnc @CBTNetwork @BenjaminKannMD ๐ #datascience #medicalAI #womeninscience #womeninstem
Another fantastic opportunity to hear from @anahita_fathi of @ChildrensPhila about the breakthroughs in #imaging technology that enable the use of radio-phenotypes on #MRI scans in pediatric low-grade gliomas #plGG Join at 4:25 pm ET during #PedSNO2023 @NeuroOnc @CBTNetwork
ICYMI - FIREFLY-1 as presented at #ASCO23:
โ
67% ORR + 93% CBR in 69 heavily pre-tx RANO-HGG evaluable pts
โ
โฌ๏ธ of durable tumor reduction w/ tovorafenib monotx in heavily pre-tx pts
โ
Rolling submission of NDA to FDA started by @DayOneBio; expected done 10/23
#btsm #pLGG
Discussing the FIREFLY-1 pediatric low-grade glioma data with Day One Bio at #ASCO23. Full video: https://t.co/KEWYOU1Rli
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