Top Tweets for #paTHophysThursday
For #paThophysThursday a short summary of the stages of sepsis and natural progression of severe disease
Steroids are often reluctantly given due to their immunosuppressive effects. For this #PaTHoPhysThursday, check out this great tweet on some common clinical scenarios in which they could be helpful.
Steroids are generally classified as “immunosuppressive”.
Yet, in select situations, we can use their properties to help tamp down inflammation in acute infections, and the risk/benefit ratio is in favor of using them even if the patient has an ongoing infection.
👇👇👇
For this #PaTHoPhysThursday, let’s briefly discuss cardiac risk in perioperative management.
A 66-year-old man presents for preoperative evaluation before R tibial plateau fracture surgical repair. He has a history of HTN and COPD...
(1/x)
For this #paTHophysThursday, let’s talk about obesity.
You have a 55-year-old patient with no prior PMH who has been struggling to lose weight for several years. He has tried dietary changes (including seeing a nutritionist) and lifestyle changes, but without success.
(1/x)
For this #paTHophysThursday, we’d like to start our #JournalClubSeries. Cardiogenic shock, defined as low cardiac output resulting in clinical and biochemical manifestations of end-organ hypoperfusion, is associated with substantial morbidity and mortality. (1/x)
For this #paTHophysThursday, check out this excellent brief overview on guideline-directed medical therapy for HFrEF.
Courtesy of @COREIMpodcast
1/ 🚨New Episode🚨
Guideline-Directed Medical Therapy in HFrEF: #5Pearls Segment
🎧 : https://t.co/C5ojMth45a
Show Notes: https://t.co/xkddqY9pi6
CME/MOC: https://t.co/C1bbGodTur
Sponsor: @ambossmed
On this somber day in the world, we’d like to first extend our thoughts and prayers to the people of Ukraine. May humanity someday reach the ever-elusive goal of world peace.
With that, let’s change it up for this #paThophysThursday and incorporate some obstetric care.
(1/x)
It’s #paThophysThursday or maybe #tHEMEsday! As we approach the end of this week, we’re gonna tie these two together with some hematology pathophysiology! @TempleHeme
So, what is pernicious anemia?
For #paThophysThursday, check out this great tweetorial on the data for uses of SGLT2 inhibitors in patients with various diseases, and how they are recommended for by many societies for patients with and without diabetes.
https://t.co/fgJwA19xdW
1/ #tweetorial SGLT2 inhibitor literature has boomed over the past 6 years demonstrating benefit of SGLT2 inhibitors in T2DM, CKD, HFrEF, and HFpEF. Let's take a look!
For #paThophysThursday, have you ever wondered why statins are usually prescribed to be taken at night? Check out this interesting tweetorial! It’s full or physiology and data behind this idea
https://t.co/VXB654sgW0
1/15
Why are statins administered at night?
In this tweetorial I'll discuss the mechanistic and historical reasons for the frequently used QHS dosing schedule. And why it's often unnecessary.
But before we get there, I'm curious: when do you prescribe/order/take statins?
For #PaThophysThursday, check out this great tweetorial on the pathophys of calcineurin inhibitor adverse effects. Remember calcineurin inhibitors are medications like cyclosporine and tacrolimus you may have seen organ transplant recipients taking.
https://t.co/ZdJfYDe5dT
1/
A brief #tweetorial on the calcineurin inhibitors #CNI and their toxicities. Let's start with a quick poll.
Which of the following describes the main mechanism of action of #CNI?
For #paThophysThursday, check out this great tweetorial reviewing general physiology of fevers. It also links to other great tweetorials later in the thread that are a deep dive into fever physiology!
https://t.co/W30c8izrGs
Why is fever considered to be ≥ 100.4 F?
A wonderful Tweetorial by @JennyShihMD, reviewed by @AvrahamCooperMD and @AdamRodmanMD.
It’s #paThophysThursday! Today, we’re admitting a patient with a chief complaint of epigastric abdominal pain. She’s 45 years old, has a history of alcohol use disorder, diabetes, and obesity. The pain radiates to the back, and this is the CT abdomen from the ED:
This is a great #paThophysThursday thread that explains why ALP is elevated with biliary obstruction, but not with direct hepatocyte injury!
1/11
Why is alkaline phosphatase elevated in biliary obstruction?
This question was debated for decades. The current explanation is NOT what I had expected.
Will you be surprised too?
This is an excellent cardiology focused thread for #paThophysThursday about wide complex tachycardias
1/ #tweetorial
Never Mistake VT for SVT with Aberrant Conduction - Key Points
➡️ A wide-complex tachycardia (WCT) is defined as:
👉 ventricular rate > 100 beats per minute
👉 QRS complex duration of more than 0.12 seconds
https://t.co/WEzYNdGlno
#medtwitter #CardioTwitter
It's Thursday, and today we have a combo #ThingsWeDoForNoReasonThursday and #paThophysThursday for your enjoyment! Let's start with case. You are seeing a 45 y/o woman in clinic doing a med rec.
For #paThophysThursday check out this amazing thread on the significance of ANAs. We see them ordered all the time, but why, and what do they mean?
1/ Understanding #ANA #tweetorial a collab w/ @MithuRheum
You are seeing a 30yo patient in the clinic who is ? an elevated ANA titer. A few months ago she had 2 weeks of joint pains & a rash. As part of the evaluation, an ANA was+ with a titer of 1:80. What do you do next?
It’s #PaThophysThursday! Today’s case is a 61 y/o woman with history of CKD, CAD presenting with chest pain and ischemic changes on EKG. Cardiology recommends a cardiac cath. Are there any medications you could give her before the procedure to reduce her risk of postop AKI?
For today’s #paThophysThursday, we know you’ve heard that elevated levels Triglycerides are associated with pancreatitis. But do you know why? Check out this great thread for a very detailed biochemical explanation!
https://t.co/EbU6qlVysB
1/🧵
Ever wonder why severe hypertriglyceridemia causes acute pancreatitis?
Are triglycerides themselves toxic to the pancreas or is there something else going on?
#tweetorial #medtwitter
As a reminder our loose curriculum is: #MicroMonday, #TachyTuesday, #WildcardWednesday, #paThophysThursday or #ThingsWeDoForNoReasonThursday, and #FOAMedFriday.
Please follow along and participate!
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