Top Tweets for #polygenicity
Two magnificent studies led by @ClaraMoreau9 investigate #polygenicity and #pleiotropy using functional connectivity in 4 psychiatric conditions, 15 CNVs (rare-variants), and 7 polygenic scores (common variants). Tour de force!!! Landmark studies!!!
✨✨We are thrilled to share 2 new papers published this week in:
#BiologicalPsychiatry: Genetic heterogeneity shapes brain connectivity in psychiatry
https://t.co/X1Rb3xmU9w
#Brain: Brain connectivity mirrors genetic pleiotropy in psychiatric conditions https://t.co/8euuqaquaO
4/7 #Polygenicity: Effect sizes of CNVs on FC were correlated with their effects on cognitive ability. However, their effect sizes adjusted for the number of genes decreased from small oligogenic to large multigenic CNVs. Polygenic scores had disproportionately low effects on FC.
1/7 #Polygenicity (=multiple genetic variants associated with one condition) and #pleiotropy (=one genetic variant influencing more than one trait) are key properties of the genomic architecture of #psychiatric conditions and represent major challenges in identifying mechanisms.
New Opinion in our April issue https://t.co/cbi2BSoKXJ: Revisiting the #malaria hypothesis: accounting for #polygenicity and #pleiotropy. @ER_Ebel @LawUricchio @PetrovADmitri @StanfordPeds @StanfordMed @Stanford @TuftsUniversity
https://t.co/0Kg1pHb3nl
Drs @ER_Ebel @LawUricchio @PetrovADmitri & Elizabeth Egan discuss the #malaria #hypothesis: accounting for #polygenicity & #pleiotropy. @StanfordPeds @StanfordMed @Stanford @TuftsUniversity
https://t.co/Ahwct27VTG
#OHBM✨Do you want to learn more about #polygenicity (that one sounds easy) & #pleiotropy (ouch!) mechanisms in #psychiatric conditions? their impacts at the brain #connectivity level? {and also...why did we do weird stuff like that?} Then come to visit our (highlighted) poster✨
Our new preprint is now online! ���
#Polygenicity #Pleiotropy
'Atlas of functional #connectivity relationships across rare and common genetic variants, traits, and #psychiatric conditions'
@JacquemontSeb @pierre_bellec @ThomasBourgeron @PTenigma @meetkd007
https://t.co/t6Jjg8mm1E
Lecture 12 Disease Circuitry Dissection w/ @Zhou_Jian #GWAS #Inheritance #CommonVariants #RareVariants #LinkageAnalysis #LD #Haplotypes #Mendel #Darwin #Fisher #Polygenicity #FTOlocus #DeepSEA @OlgaTroyanskaya #VariantEffect #RegulatoryGenomics #Obesity https://t.co/NqTusNMhN5
The 2-day symposium lead by the @StanleyCenter Director will feature progress made by the #NeuroGAP scientific teams on #psychiatricgenetics, and address the challenges of turning #polygenicity into insights that can help patients @elisebrobinson @annehstevenson @KarestanKoenen
Nature Medicine’s #MentalHealth editor Kate Gao will be at the @broadinstitute @StanleyCenter symposium on Severe Mental Illness next week (https://t.co/gg5ola9fLp). Looking forward to seeing you there and learning about exciting new research!
@AgnesAyton @Dr_C_Llewellyn Sorry, that’s a polemic personal opinion piece written by a now dead author in 2003 even before #GWAS really took off and before we understood that a complex trait is influenced by thousands of genetic variants #polygenicity the guy lived in the mono/oligogenic era.
We are doing exciting things in human #neurogenetics, and we need your talent! From studying #rare diseases, to understanding common disease #polygenicity and #pleiotropy using large-scale approaches, there’s a project for you! Drop us a line.
Anti-reductionistic sober view of the neurobiology of #psychiatric disease by Steve Hyman https://t.co/qynGpaFeDy and call for new cartography of mental illness #polygenicity
Last Seen Hashtags on Sotwe
Most Popular Users
Elon Musk 
@elonmusk
241M followers
Barack Obama
@barackobama
119.2M followers
Cristiano Ronaldo
@cristiano
112.1M followers
Donald J. Trump
@realdonaldtrump
111.8M followers
Narendra Modi
@narendramodi
107.1M followers
Rihanna
@rihanna
98.1M followers
NASA
@nasa
92.2M followers
Justin Bieber
@justinbieber
91.3M followers
KATY PERRY
@katyperry
88.5M followers
Taylor Swift
@taylorswift13
82.4M followers
Lady Gaga
@ladygaga
73.9M followers
Virat Kohli
@imvkohli
71.2M followers
Kim Kardashian
@kimkardashian
70.2M followers
YouTube
@youtube
68.7M followers
Bill Gates
@billgates
64.4M followers
Neymar Jr
@neymarjr
64.1M followers
The Ellen Show
@theellenshow
62.4M followers
CNN
@cnn
61.8M followers
Selena Gomez
@selenagomez
61.6M followers
X
@x
60.8M followers