Top Tweets for #transgenicmodel
One quality control method our experts have mastered is the use of southern blot analysis to exclude F1 mice with random insertions. Learn more about our rigorous QC methods: https://t.co/6BZ8erBS9z #geneediting #mousemodel #crispr #transgenicmodel #genetargeting
Genetically modified animal models are trusted tools for answering important research questions. However, current methods for generating such models can trigger off-target modifications.
This study highlights the mechanistic role of neCtnnb1 in neocortical expansion and development. Click to learn more: https://t.co/s0gAfoPLDo
#publication #geneediting #mousemodel #immunodeficient #crispr #transgenicmodel #genetargeting #celllinedevelopment #geneticengineering
Canonical Wnt/β-catenin signaling is essential for neocortical development. A recent publication featuring our custom mouse model identified that knock-out of the enhancer, neCtnnb1, controlled canonical Wnt signaling via transcriptional regulation of Ctnnb1.
W/ 800+ projects completed per year, our gene editing team has the experience & expertise to create your model of choice in industry-leading timelines, so you can focus on downstream applications👉
https://t.co/nKGKmURaM0 #geneediting #mousemodel #crispr #transgenicmodel #biotech

Our proprietary CRISPR-based Extreme Genome Editing platform promotes Homology Directed Repair (HDR) over Non-homologous End Joining (NHEJ), increasing large fragment knockin efficiency by up to 20 fold👉https://t.co/CxRgD7nEAg #geneediting #mousemodel #crispr #transgenicmodel

Our large collection of off-the-shelf humanized mouse models accelerate the process of antibody drug discovery. Learn more about our capabilities👉https://t.co/vgRScwnvOi #mousemodel #antibodydiscovery #therapeutics #geneediting #crispr #transgenicmodel #genetargeting
In this setting, targeting known “safe harbor” loci, such as Rosa26 can eliminate the possibility that the gene will integrate in an unpreferred location in the genome & result in silencing or expression issues👉https://t.co/ZbeJ5x2UmG #geneediting #transgenicmodel #genetargeting

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