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The main argument is that "its not really worth the squeeze" Even in the studies that seperate intentional vs unintentional weight loss in the obese, the benefit in ACM is like 10-20% and mostly on the lower end But those studys are all over the place, some say its more, some say way less, some say no effect at all and some say its straight up negative Obesity paradox with no cancer/with cancer wouldnt play a huge role in this argument, since were talking longevity, but the below chart is from another study with the top curve being 70 year olds and the curves below being 60, 50 etc The studies that "disprove" the obesity paradox all have issues because theyre partly based on questionnaires and also select for naturally better metabolisms as the control (="never obese in lifetime") and of course those live longer BMI isn perfect, but most of those studies are pretty old and nobody was fat back then so BMI actually works quite well At the same time, studies that looked at rapid weight loss are almost always negative for longevity At the same time the anecdotal stuff with ER/ICU docs and fatties doing better Based on this, I think its pretty rational to absolutely not sweat weightloss (literally) in his specific case because hes already obese and elderly Getting it off would likely have some longevity benefits but theyre not that large and its actually not fully clear if its just benefits

That is the point though Kruse found out "what adipose tissue is doing to him" And its really not that bad at all tbh 10%ish effect on ACM isnt nothing, but its also really not a big deal Especially with all of these studies being completely all over the fucking place That is SPECIFICALLY for him (=older age and ALREADY overweight) Obviously, it's likely better to not ever get to that But thats not reality.