Incredibly excited to share my PhD work published in @ScienceAdvances today.
For the first time, we have identified 1) a biological role of ADO AND 2) unexpected mechanism of essentiality that is unique to cancer cells.
https://t.co/modZpntoHS
(1/n)
@UofTIMS@PMResearch_UHN
Curbing cancer cells’ metabolism 🧫
A study led by Dr.@MKoritzinsky@UHN found that an enzyme, ADO, is critical to keep the balance between the production and elimination of reactive oxygen species in cancer cells, protecting them from oxidative stress.
https://t.co/5qWtQ5a9W0