HKU Stroke

Innovate solutions, empower lives and inspire changes to alleviate the burden of stroke.

[HKU Stroke @hkustroke]

The TRICH score, by @HKUStroke, promotes upfront triple antihypertensive-use after ICH. We are committed to further research to support its implementation in practice, improving patients’ blood pressure control and long-term vascular outcomes.
https://t.co/9ki6wGeLZR

[HKU Stroke @hkustroke]

SmartRehab wins a Gold Medal with Congratulations of the Jury at the 49th International Exhibition of Inventions Geneva! More details of our project: https://t.co/L4B19p3lTt

[HKU Stroke @hkustroke]

Our recent research paper on ‘Location-specific hematoma volume cutoff and clinical outcomes in intracerebral hemorrhage’ has been featured on #BloggingStroke by @StrokeAHA_ASA Read the blog post: https://t.co/XLL8S34U2t #intracerebralhemorrhage #stroke #hematomavolume @hkustroke

[HKU Stroke @hkustroke]

@hkumed develops AI-powered SmartRehab platform to provide
an accessible and affordable rehabilitation strategy
for stroke patients globally, especially in low- and middle-income countries, with limited rehabilitation services
For more: https://t.co/yjVwx7kZ0i
@hkustroke

[HKU Stroke @hkustroke]

@FZMarques @HyperAHA A: This could be due to differences in several factors, including ethnicities, sample size and adjustment of different covariates. We would be very interested in collaborating with you to further investigate this. @hkustroke @HyperAHA #HYPHIP

[Prof Francine Marques @FZMarques]

I have many questions about this paper🙋‍♀️

In our study, we didn't see a major difference in bacterial taxa between healthy controls & HTN patients, but we saw a difference in microbiome pathways https://t.co/HhODUwK6Ar

I was wondering if you examined those?

#HYPHIP @HyperAHA

[HKU Stroke @hkustroke]

@tiagojcosta_ @AnastasiaSMihai @GQworks @HyperAHA @fjorios Thank you @tiagojcosta_ and @fjorios. Metagenomic sequencing in larger cohorts is required to identify bacterial species associated with 24h BP, which may lead to novel/ improved and personalized microbiome-based therapy. @HyperAHA @hkustroke @AnastasiaSMihai @PreDVirwani

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q9 While you excluded those on anti-hypertensive medication, could you inform us how do the different types regulate gut microibiome & whether this is sex specific as well?
@hkustroke @GQworks #HYPHIP @HyperAHA

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q8b - From @guto_montezano
What was the rationale behind only recruiting subjects with Chinese ethnicity?
@hkustroke @GQworks #HYPHIP @HyperAHA

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q8a - @hkustroke @GQworks you selected Chinese men & women & could you advise whether these sex differences are specific for this ethnicity? #HYPHIP
@HyperAHA

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q7 - @hkustroke @GQworks you selected Chinese men & women & could you advise whether these sex differences are specific for this ethnicity #HYPHIP @HyperAHA

[Francisco Rios @fjorios]

Q7. @hkustroke @GQworks. I found very interesting that your data suggest enrichment of LPS producing species. Can it be associated with increased gut inflammatory response? Are there any data related to this observation in sex differences? #HYPHIP @HyperAHA @AnastasiaSMihai

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q7 - @hkustroke @GQworks your participants were also a within a similar range for BMI < 30 & given the increasing prevalence of obesity, how would adiposity impact the gut microbiome? #HYPHIP @HyperAHA

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q6 - @hkustroke @GQworks your participants were in a specific age range of 40 - 65 years & given the increasing aging population, could you advise what is know about the gut microbiome in our elders & also young <40 yrs age?

#HYPHIP @HyperAHA #HYPHIP

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q5 @hkustroke @GQworks #HYPHIP @HyperAHA

[Gordon Qian @GQworks]

@AnastasiaSMihai @fjorios @HyperAHA @hkustroke A4.2 The dietary profile across the cohort was actually quite homogeneous with no obvious clusters forming when performing dimensionality reduction. #HYPHIP
@HyperAHA

[Gordon Qian @GQworks]

@AnastasiaSMihai @fjorios @HyperAHA @hkustroke A4. Yes, weekly dietary intake was logged by a trained research personnel. You can can find more details in the supplementary methods. No obvious difference in dietary profiles was observed across the whole cohort and across genders. #HYPHIP
@HyperAHA

[Francisco Rios @fjorios]

Q4. It is a very interesting data. Can you explain to us if there are some differences in diet or any environmental differences in the population @HyperAHA #HYPHIP
@GQworks @hkustroke @AnastasiaSMihai

[Tiago J. Costa @tiagojcosta_]

Q3 It's quite intriguing that dysregulation in GM appears to have a stronger association with hypertension in women. Could there be any correlation with sex hormones? @HyperAHA #HYPHIP @GQworks @AnastasiaSMihai @hkustroke

[Dr Anastasia Mihailidou FAHA FCSANZ FESC @AnastasiaSMihai]

Q2b - From @guto_montezano What was the rationale behind only recruiting subjects with Chinese ethnicity? @hkustrok @GQworks #HYPHIP @HyperAHA